ID D7T835_VITVI Unreviewed; 108 AA.
AC D7T835;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Mitochondrial pyruvate carrier {ECO:0000256|RuleBase:RU363100};
GN OrderedLocusNames=VIT_19s0090g01180 {ECO:0000313|EMBL:CBI26694.3};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CBI26694.3, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- FUNCTION: Mediates the uptake of pyruvate into mitochondria.
CC {ECO:0000256|ARBA:ARBA00002429, ECO:0000256|RuleBase:RU363100}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448,
CC ECO:0000256|RuleBase:RU363100}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU363100}.
CC -!- SIMILARITY: Belongs to the mitochondrial pyruvate carrier (MPC) (TC
CC 2.A.105) family. {ECO:0000256|ARBA:ARBA00006416,
CC ECO:0000256|RuleBase:RU363100}.
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DR EMBL; FN595751; CBI26694.3; -; Genomic_DNA.
DR RefSeq; XP_002277248.1; XM_002277212.4.
DR AlphaFoldDB; D7T835; -.
DR STRING; 29760.D7T835; -.
DR PaxDb; 29760-VIT_19s0090g01180-t01; -.
DR EnsemblPlants; Vitvi19g00566_t001; Vitvi19g00566_P001; Vitvi19g00566.
DR GeneID; 100265792; -.
DR Gramene; Vitvi19g00566_t001; Vitvi19g00566_P001; Vitvi19g00566.
DR KEGG; vvi:100265792; -.
DR eggNOG; KOG1589; Eukaryota.
DR HOGENOM; CLU_099502_1_2_1; -.
DR InParanoid; D7T835; -.
DR OMA; FHIWRYK; -.
DR OrthoDB; 590256at2759; -.
DR Proteomes; UP000009183; Chromosome 19.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006850; P:mitochondrial pyruvate transmembrane transport; IBA:GO_Central.
DR InterPro; IPR005336; MPC.
DR PANTHER; PTHR14154:SF2; MITOCHONDRIAL PYRUVATE CARRIER 2; 1.
DR PANTHER; PTHR14154; UPF0041 BRAIN PROTEIN 44-RELATED; 1.
DR Pfam; PF03650; MPC; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW ECO:0000256|RuleBase:RU363100};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792,
KW ECO:0000256|RuleBase:RU363100};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363100}.
SQ SEQUENCE 108 AA; 12136 MW; 23BDF5E1E2424963 CRC64;
MGASKLQALW NHPAGPKTIH FWAPTFKWGL SIANVADFSK PPETLSYPLQ IVVACSGLIW
SRYGMVITPR NWNLFSVNLA MAGTGMYQLS RKIQHDYHSK TEAEITNE
//
