ID D7TK89_VITVI Unreviewed; 802 AA.
AC D7TK89;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN OrderedLocusNames=VIT_10s0003g03710 {ECO:0000313|EMBL:CBI30911.3};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CBI30911.3, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; FN595992; CBI30911.3; -; Genomic_DNA.
DR AlphaFoldDB; D7TK89; -.
DR STRING; 29760.D7TK89; -.
DR PaxDb; 29760-VIT_10s0003g03710-t01; -.
DR EnsemblPlants; Vitvi10g00816_t001; Vitvi10g00816_P001; Vitvi10g00816.
DR Gramene; Vitvi10g00816_t001; Vitvi10g00816_P001; Vitvi10g00816.
DR eggNOG; KOG2167; Eukaryota.
DR HOGENOM; CLU_004747_7_2_1; -.
DR InParanoid; D7TK89; -.
DR OMA; NYQEQTW; -.
DR Proteomes; UP000009183; Chromosome 10.
DR ExpressionAtlas; D7TK89; baseline and differential.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF123; CULLIN-4; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 446..675
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 92026 MW; 286F61915F24DF66 CRC64;
MKKAKSQAVA CSLDPKNGLQ PPPHPPPPSS HHFPDDDFDP SAMALDDDLK PDDADAAACS
RPSAGGVTAN LSRKKATPPQ PAKKQLVIKL LKAKPTLPTN FEEDTWAKLK SAISAIFLKQ
PDPCDLEKLY QAVNDLCLHK MGGNLYQRIE KECESHIRAA LQSLVGQSPD LVVFLSLVEK
CWQDLCDQML MIRGIALYLD RTYVKQTPNV RSLWDMGLQL FRKHLSLSPE VEHKTVTGLL
RMIERERLGE AVDRTLLNHL LKMFTALGIY LESFEKPFLE CTSEFYAAEG MKYMQQSDVP
DYLKHVEIRL HEEHERCLLY LDASTRKPLV ATAERQLLER HISAILDKGF MMLMDGNRIE
DLQRMYLLFS RVNALESLRQ ALSSYIRRTG QGIVMDEEKD KDMVSCLLEF KASLDTIWEE
SFSRNEAFCN TIKDAFEHLI NLRQNRPAEL IAKFLDEKLR AGNKGTSEEE LEGTLDKVLV
LFRFIQGKDV FEAFYKKDLA KRLLLGKSAS IDAEKSMITK LKTECGSQFT NKLEGMFKDI
ELSKEINESF KQSSQARTKL PTGIEMSVHV LTTGYWPTYP PMDVRLPHEL NVYQDIFKEF
YLSKYSGRRL MWQNSLGHCV LKAEFPKGKK ELAVSLFQTV VLMLFNDAQK LSFQDIKDST
GIEDKELRRT LQSLACGKVR VLQKLPKGRE VEDDDSFMFN EGFTAPLYRI KVNAIQMKET
VEENTSTTER VFQDRQYQVD AAIVRIMKTR KVLSHTLLIT ELFQQLKFPI KPADLKKRIE
SLIDREYLER DKNNPQIYNY LA
//
