ID D7TMQ9_VITVI Unreviewed; 565 AA.
AC D7TMQ9;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=Flap endonuclease GEN-like 2 {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=VIT_16s0100g01300 {ECO:0000313|EMBL:CBI31782.3};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CBI31782.3, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; FN596000; CBI31782.3; -; Genomic_DNA.
DR RefSeq; XP_002263340.2; XM_002263304.4.
DR AlphaFoldDB; D7TMQ9; -.
DR STRING; 29760.D7TMQ9; -.
DR PaxDb; 29760-VIT_16s0100g01300-t01; -.
DR EnsemblPlants; Vitvi16g01007_t001; Vitvi16g01007_P001; Vitvi16g01007.
DR GeneID; 100256642; -.
DR Gramene; Vitvi16g01007_t001; Vitvi16g01007_P001; Vitvi16g01007.
DR KEGG; vvi:100256642; -.
DR eggNOG; KOG2519; Eukaryota.
DR HOGENOM; CLU_013777_2_1_1; -.
DR InParanoid; D7TMQ9; -.
DR OMA; NKSHCAM; -.
DR OrthoDB; 26655at2759; -.
DR Proteomes; UP000009183; Chromosome 16.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd09869; PIN_GEN1; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR InterPro; IPR006085; XPG_DNA_repair_N.
DR PANTHER; PTHR11081:SF54; FI23547P1; 1.
DR PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR Pfam; PF00867; XPG_I; 1.
DR Pfam; PF00752; XPG_N; 1.
DR PRINTS; PR00853; XPGRADSUPER.
DR SMART; SM00279; HhH2; 1.
DR SMART; SM00484; XPGI; 1.
DR SMART; SM00485; XPGN; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183}.
FT DOMAIN 1..97
FT /note="XPG N-terminal"
FT /evidence="ECO:0000259|SMART:SM00485"
FT DOMAIN 130..200
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
FT REGION 427..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 565 AA; 62944 MW; 629E33B403409005 CRC64;
MGVKNLWDIL ESCKKTLPLY HLQNKRVCID LSCWMVQLQN VNKSHASIKD KLYLKGLFHR
LRALIALNCS LLFVTDGSIP AIKLATYRRR LNSGTEVTRD ETNSHNVPSL RRNMGSEFSC
MIKEAKVLGL ALGIPCLDGI EEAEAQCALL NSESLCDGCF TSDSDVFLFG ARTVYRDICL
GEGGYVVCYE MADIESTLGF GRNSLITLAL LLGSDYSQGV HGFGPESACQ IVKSVGEEVV
LKKIALEGIS FAKKSKGSRK QGQVLKCNDK ENCSDHEMNI NGSEHSSQRE FLRVIDAYLK
PKCHSADSDA VHRALALLPF QRTEAQKICA QLFEWPPEKT DEYILPKIAE RDLRRFANLR
STSSNLGIHF PLHEIPVKCP ISGIIKHRKV QGRECFEVSW EEFDGLKSSI IPAELVKSAC
PEKIVEFEGR KPQEKKQNHR KPRPKKSNNR TPLAEIDKQL QNLLLDIESG GNSFQNVSFS
SSMTPSKTQI DATKAAKTQY MLLDTESESD NDNHNEAIIC HQNGRCGAEI VIDLLSPSPA
IRARKVSKCQ QGNNGQQIDV IDLSD
//
