ID D7U343_VITVI Unreviewed; 419 AA.
AC D7U343;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 24-JAN-2024, entry version 75.
DE RecName: Full=BRCA1-associated RING domain protein 1 {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=VIT_07s0005g03940 {ECO:0000313|EMBL:CBI37160.3};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CBI37160.3, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FN596502; CBI37160.3; -; Genomic_DNA.
DR AlphaFoldDB; D7U343; -.
DR STRING; 29760.D7U343; -.
DR PaxDb; 29760-VIT_07s0005g03940-t01; -.
DR eggNOG; KOG4362; Eukaryota.
DR HOGENOM; CLU_025968_1_0_1; -.
DR InParanoid; D7U343; -.
DR OMA; CIVGHED; -.
DR Proteomes; UP000009183; Chromosome 7.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd17734; BRCT_Bard1_rpt1; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031099; BRCA1-associated.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13763:SF9; BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1; 1.
DR PANTHER; PTHR13763; BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR SMART; SM00292; BRCT; 2.
DR SUPFAM; SSF52113; BRCT domain; 2.
DR PROSITE; PS50172; BRCT; 2.
DR PROSITE; PS51805; EPHD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 38..158
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 212..284
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 305..419
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
SQ SEQUENCE 419 AA; 46588 MW; ACAE4C51783C6B65 CRC64;
MSYSGNGLIF SSNLESKHIG SISGPHLRSN SGSSDVKEIV CGFCQSSKLS MATGPMLHYA
NGKPVQSSNI FDSNVIHVHK KCVDWAPRVY YAGETIINLE KELERSGQLE CSGCGLKGAA
LGCYMKHCRK SFHVLCAMKI LHCRWDFENF LMFCPSHSSL KFPSEKSQFG EKSTKNNSKS
TQMYISYSFN CCCGVTEWVL CGSALSTKEK FLLVKFGETI CVSVSKYWNP NVTHVITATD
VNGACCRTIK VLMAILHGGW ILKIDWVKAC MEALYLVDEE PYEVSLDNYG CRDGPKTGRL
RSLDNAPKLF KDLIFYFIGD FVPTYKIDLV DLIRAAGGFV LACKNKLVAQ VHDGRIAPST
ALVVYNLEPP QGSMLREDDP VMLWKREAEV LAAMIGSHVI SDRWILDSIA ACRLQPFTL
//
