ID   D7U509_VITVI            Unreviewed;       896 AA.
AC   D7U509;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   24-JAN-2024, entry version 67.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN   OrderedLocusNames=VIT_03s0038g02830 {ECO:0000313|EMBL:CBI37828.3};
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760 {ECO:0000313|EMBL:CBI37828.3, ECO:0000313|Proteomes:UP000009183};
RN   [1] {ECO:0000313|Proteomes:UP000009183}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX   PubMed=17721507; DOI=10.1038/nature06148;
RG   The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA   Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA   Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA   Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA   Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA   Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA   Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA   Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA   Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA   Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA   Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA   Wincker P.;
RT   "The grapevine genome sequence suggests ancestral hexaploidization in major
RT   angiosperm phyla.";
RL   Nature 449:463-467(2007).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the importin beta family. Importin beta-2
CC       subfamily. {ECO:0000256|ARBA:ARBA00038423}.
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DR   EMBL; FN596508; CBI37828.3; -; Genomic_DNA.
DR   AlphaFoldDB; D7U509; -.
DR   STRING; 29760.D7U509; -.
DR   PaxDb; 29760-VIT_03s0038g02830-t01; -.
DR   EnsemblPlants; Vitvi03g00180_t001; Vitvi03g00180_P001; Vitvi03g00180.
DR   Gramene; Vitvi03g00180_t001; Vitvi03g00180_P001; Vitvi03g00180.
DR   eggNOG; KOG2023; Eukaryota.
DR   HOGENOM; CLU_008136_1_0_1; -.
DR   InParanoid; D7U509; -.
DR   OMA; AQEGAMS; -.
DR   Proteomes; UP000009183; Chromosome 3.
DR   ExpressionAtlas; D7U509; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR   GO; GO:0008139; F:nuclear localization sequence binding; IBA:GO_Central.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000357; HEAT.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527:SF3; FI21453P1-RELATED; 1.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   Pfam; PF02985; HEAT; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          34..102
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
FT   REGION          320..352
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        331..352
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   896 AA;  99667 MW;  DDBF2D65BE1B12B6 CRC64;
     MAATASWQPQ EEGFNSICAL LQHQISPSSD KSQIWQQLQH FSHFPDFNNY LVFILARAEG
     QSVEVRQAAG LLLKNNLRTA FNSMTPAYQL YIKSELLPCL GAADRHIRST AGTIITVLVQ
     LGGVSGWPEL LQTLANCLES NDLNHMEGAM DALSKICEDV PQVLDSDVPG LVEHPINLFL
     PKLFQFFQSP HASLRKLSLG SVNQYIMLMP AALFASMDQY LQGLFVLAHD SAAEVRKLVC
     AAFVQLIEVN PSFLEPHLRN VIEYMLQVNK DSDDEVALEA CEFWSAYCDA QLPLENLREF
     LPRLIPVLLS NMAYAEDDES LAEAEEDESL PDRDQDLKPR FHSSRFHGSD NAEDDDDDIV
     NIWNLRKCSA AGLDVLSNVF GDEILPTMMP IVQAKLSTTD DETWKEREAA VLALGAVAEG
     CITGLYPHLS EIVTFIIPLL DDKFPLIRSI SCWTLSRFSR FVVQGIGHQK GSEQFDKVLR
     GLLRRILDTN KRVQEAACSA FATLEEEAAE KLAPHLEIIL QHLMCAFGKY QRRNLRIVYD
     AIATLADAVG EKLNQPTYLD ILMPPLIAKW QQLSNSDKDI FPLLECFTSI AQALGTGFSQ
     FAEPVFQRCI NIIQTQQLAK IDPASAGVQY DKEFIVCSLD LLSGLAEGLG SGIESLVAQS
     SLRDLLLQCC MDDDAPDVRQ SAFALLGDLA RVCPVHLHPR LSDFLNVAAK QLNTSKLKET
     VSVANNACWA IGELAVKVHQ EVSPIVMTVI SCLVPILQHA EELNKSLIEN SAITLGRLAW
     VCPEIVSLHM EHFMQSWCTA LSMIRDDIEK EDAFRGLCAM VRANPSGALS SLVYMCKAIA
     SWHEIRSEDL HNEVCQVLHG YKQMLRNGAW EQCMSALEPP VKDKLSKYQV LVGTII
//