ID D7UCW9_VITVI Unreviewed; 1083 AA.
AC D7UCW9;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 24-JAN-2024, entry version 75.
DE RecName: Full=Bifunctional fucokinase/fucose pyrophosphorylase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=VIT_15s0046g00110 {ECO:0000313|EMBL:CBI40584.3};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CBI40584.3, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SIMILARITY: Belongs to the GHMP kinase family.
CC {ECO:0000256|ARBA:ARBA00038121}.
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DR EMBL; FN596755; CBI40584.3; -; Genomic_DNA.
DR RefSeq; XP_010661973.1; XM_010663671.2.
DR AlphaFoldDB; D7UCW9; -.
DR STRING; 29760.D7UCW9; -.
DR PaxDb; 29760-VIT_15s0046g00110-t01; -.
DR EnsemblPlants; Vitvi15g00932_t001; Vitvi15g00932_P001; Vitvi15g00932.
DR GeneID; 100258719; -.
DR Gramene; Vitvi15g00932_t001; Vitvi15g00932_P001; Vitvi15g00932.
DR KEGG; vvi:100258719; -.
DR eggNOG; KOG4644; Eukaryota.
DR HOGENOM; CLU_006983_1_1_1; -.
DR InParanoid; D7UCW9; -.
DR OMA; QKMFSYC; -.
DR OrthoDB; 5800at2759; -.
DR BRENDA; 2.7.7.30; 6671.
DR Proteomes; UP000009183; Chromosome 15.
DR ExpressionAtlas; D7UCW9; baseline and differential.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0050201; F:fucokinase activity; IBA:GO_Central.
DR GO; GO:0042352; P:GDP-L-fucose salvage; IBA:GO_Central.
DR Gene3D; 3.30.230.120; -; 1.
DR InterPro; IPR012887; Fucokinase.
DR InterPro; IPR001174; Galkinase.
DR InterPro; IPR013750; GHMP_kinase_C_dom.
DR InterPro; IPR036554; GHMP_kinase_C_sf.
DR InterPro; IPR006204; GHMP_kinase_N_dom.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR PANTHER; PTHR32463; L-FUCOSE KINASE; 1.
DR PANTHER; PTHR32463:SF0; L-FUCOSE KINASE; 1.
DR Pfam; PF07959; Fucokinase; 1.
DR Pfam; PF08544; GHMP_kinases_C; 1.
DR Pfam; PF00288; GHMP_kinases_N; 1.
DR PRINTS; PR00960; LMBPPROTEIN.
DR SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 146..544
FT /note="L-fucokinase"
FT /evidence="ECO:0000259|Pfam:PF07959"
FT DOMAIN 841..905
FT /note="GHMP kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00288"
FT DOMAIN 985..1058
FT /note="GHMP kinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08544"
SQ SEQUENCE 1083 AA; 119201 MW; 726304BA5F8CC413 CRC64;
MESRRSRAKV DLTGILRKSW YRLRLSVRHP SRVPTWDAIV LTAASPEQAE LYEWQLKRAK
RLGRIASSTV TLVVPDPDGN RIGSGGATLN AIYALARHLE ALGPQVENMD TGSSESSVPH
ERSNSEVSFS PMVSFMAKRH ILLLHAGGDS KRVPWANPMG KVFLPLPYLA ADDPDGPVPL
LFDHILAISC CARQAFKNEG GIFIMTGDVL PCFDASTMVL PEDTSCIITV PLTLDIASNH
GVIVASKTGI LNKTSYVSLV ENLLQKPTME ELVKNQAILD DGRTLLDTGI IAVRGKAWVE
LVRLACSSQP MIADLLKSKK EMSLYEDLVA AWVLARHEWL RLRPLGEELI NRLGKQKMYS
YCAYDLLFLH FGTSSEVLDH LSGADSGLVG RRHLCSVPAT TVSDIAASAV VISSKIAPSV
SIGDDSIVYD SSISGGIQIG SQSIVVGVNV PGDSNGIEDN GFRFILPDRH CLWEVPLVGC
TGRVIVYCGL HDNPKDSLSR NGTFCGKPWD KVLHDLGIQE GDLWSTRSTH EKCLWNAKIF
PILSYFEMLS LAAWLMGLND QKTKSLLPLW KSSQRVSLEE LHRSIDFPHM CIGSSNHQAD
LAAGIAKACI NYGLLGRNLS QLCEEILQKD VSGVKICKDL LDQCSNLQGQ NSKILPKSRA
YQVQVDLLQA CREEKMACKL EHKVWAAVAD ETAAAVRYGF RERVLESSNS TSASAYQSSA
FDGCVDQSFR HRDVRIELPV RVDFVGGWSD TPPWSLERAG CVLNMSIKLD DCAPVGTSIT
TTEQTGIEIN DDDTINKVYI EDPTSITTPF NSNDPFRLVK SALLVTGVTR DKLLLSMGLQ
IHTWTGVPRG TGLGTSSILA AAVVKGLLKI TNRDDSNEIV ARLVLVLEQL MGTGGGWQDQ
IGGLYPGIKF TESFPGVPLK LQVIPLMASP QLISDLQQRL LVVFTGQVRP ARRVLEKVVT
RYLRRDNLLI SSIKRLAELA RMGREALMNC DLDELGEIML EAWRLHQELD PYCSNTFVDR
LFELADPFCC GYKLVGAGGG GFALLLAKDA DSAKKLRDLL QKDPHLEEYG SEFEVKIYNW
ALF
//
