ID D7UWH1_LISGR Unreviewed; 714 AA.
AC D7UWH1;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Ricin-type beta-trefoil lectin domain protein {ECO:0000313|EMBL:EFI84872.1};
GN ORFNames=HMPREF0556_11425 {ECO:0000313|EMBL:EFI84872.1};
OS Listeria grayi DSM 20601.
OC Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX NCBI_TaxID=525367 {ECO:0000313|EMBL:EFI84872.1, ECO:0000313|Proteomes:UP000010119};
RN [1] {ECO:0000313|EMBL:EFI84872.1, ECO:0000313|Proteomes:UP000010119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20601 {ECO:0000313|EMBL:EFI84872.1,
RC ECO:0000313|Proteomes:UP000010119};
RA Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240, ECO:0000256|RuleBase:RU003355}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFI84872.1}.
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DR EMBL; ACCR02000003; EFI84872.1; -; Genomic_DNA.
DR RefSeq; WP_003759033.1; NZ_GL538353.1.
DR AlphaFoldDB; D7UWH1; -.
DR STRING; 525367.HMPREF0556_11425; -.
DR eggNOG; COG1404; Bacteria.
DR HOGENOM; CLU_386757_0_0_9; -.
DR Proteomes; UP000010119; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07473; Peptidases_S8_Subtilisin_like; 1.
DR CDD; cd00161; RICIN; 2.
DR Gene3D; 2.80.10.50; -; 3.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034204; PfSUB1-like_cat_dom.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR43399; SUBTILISIN-RELATED; 1.
DR PANTHER; PTHR43399:SF4; TK-SUBTILISIN; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF14200; RicinB_lectin_2; 3.
DR PRINTS; PR00723; SUBTILISIN.
DR SMART; SM00458; RICIN; 2.
DR SUPFAM; SSF50370; Ricin B-like lectins; 2.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 2.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Lectin {ECO:0000313|EMBL:EFI84872.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000010119};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..714
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003106623"
FT DOMAIN 429..567
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|SMART:SM00458"
FT DOMAIN 574..712
FT /note="Ricin B lectin"
FT /evidence="ECO:0000259|SMART:SM00458"
FT ACT_SITE 163
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 203
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 366
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 714 AA; 77901 MW; 58F15B91B0D82D7D CRC64;
MKKGYALFCS MILSIGILVT PATAQAEPNQ AMTAESKQII QTVQTAEKED YQDQRVIVTL
KDTTPAYIEE NYPLVQAEMI KTDTYLFKIK KSAGTLETLI KQLLADRTHI SIAEPNYKAT
ISSSSTDKKL WAKNNSSYPE FDINYNKIDP AQSKKKIKIA VVDTGIDYNH PALKNVISKT
KSGAVNGRDF GDNDNDPMDK DSHGTHVAGT IAGANGIGLD TNVEIMPLKV ERSDGNIYVS
DIIAAMDYAV KNKAAIVNLS LITPFKSQEM KKTIDKAKNV LFIAAAGNNG GNNDKEAGGT
NVNLMTPLYP ASFDSPNIIS VANLKQNGFL EESSNYGKTS VDLAAPGTNI YSTLPNGKYG
YKTGTSMAAP QVTGIAALLE GKYTSDSAVQ IKSRILKNVH KLSALNGKMT TGGLLDAYKA
FSPDTLTSDR YYYIRSVGSG LYMNVKGNSS KENTALWQSG MNGKAGEQWK IVKNSNGSVY
LQSRLGKVLQ LKNNSKNPNT VLQINKKNTK NNAQQFYLSK IANGRYSIES WKKQTNVAGV
SGNTKASKSA ILAKRNQESL SEQWEFKPVA IQSGKTYNLI SKKSGKALEI SSTSKLAGAK
LYQNTSKNSI SQQFILKKDS KGIQIVSKAN PKYALEIAGN KMAKRTKLSM QTQKNTKGQH
FTFKFQSDGS VTIAALSSTK YGLDVKGAST KNKTAIQLYS LKNLDNQKWF LIPR
//
