ID D7WD77_9CORY Unreviewed; 383 AA.
AC D7WD77;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN ORFNames=HMPREF0291_11765 {ECO:0000313|EMBL:EFK54108.1};
OS Corynebacterium genitalium ATCC 33030.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=585529 {ECO:0000313|EMBL:EFK54108.1, ECO:0000313|Proteomes:UP000004208};
RN [1] {ECO:0000313|EMBL:EFK54108.1, ECO:0000313|Proteomes:UP000004208}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33030 {ECO:0000313|EMBL:EFK54108.1,
RC ECO:0000313|Proteomes:UP000004208};
RA Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFK54108.1}.
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DR EMBL; ACLJ02000003; EFK54108.1; -; Genomic_DNA.
DR AlphaFoldDB; D7WD77; -.
DR STRING; 585529.HMPREF0291_11765; -.
DR eggNOG; COG1169; Bacteria.
DR HOGENOM; CLU_006493_8_6_11; -.
DR Proteomes; UP000004208; Chromosome.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:EFK54108.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004208}.
FT DOMAIN 113..373
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 383 AA; 41346 MW; 0E949467B30B5086 CRC64;
MRCLPGTLKS LLMPSPRPET APDFLLSRAS GSVRTQGTTS TFIEPWDAVA ALQRREVNMV
VGALPFDRDA PAALTVPEQI ITEAGTLQPH SYYREGPGAQ LHAAVAGYDP EPHEHLRRVE
AAVDTICNSI LDKVVLARSV DFVFDPPVDP RLVAARLIEL SSTRDGFIAD LTPAGKPGHM
IVGSSPELLI RKQGLEITSY PLAGSAPRIF DDEDADRAAG EKLYNSTKDL DEHSYVVEHI
RDILTPLCRE LTIPDRPVLD RTNEMWHLAT PIKGVLYDPA PSALDLATRL YPTPAVCGSP
QYAAEALITT AETDRSFYAG TVGWCDSHGD GEYMVSIRCA EVNGDGTAAR AWAGGGLVAA
SKPEEELAET TAKLLTIQRA LGL
//
