ID D8EYN1_9DELT Unreviewed; 340 AA.
AC D8EYN1;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Toprim domain-containing protein {ECO:0000259|Pfam:PF13662};
DE Flags: Fragment;
GN ORFNames=NPH_3673 {ECO:0000313|EMBL:EFK11376.1};
OS delta proteobacterium NaphS2.
OC Bacteria; Deltaproteobacteria.
OX NCBI_TaxID=88274 {ECO:0000313|EMBL:EFK11376.1, ECO:0000313|Proteomes:UP000003834};
RN [1] {ECO:0000313|EMBL:EFK11376.1, ECO:0000313|Proteomes:UP000003834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NaphS2 {ECO:0000313|EMBL:EFK11376.1,
RC ECO:0000313|Proteomes:UP000003834};
RX PubMed=21124915; DOI=10.1371/journal.pone.0014072;
RA Didonato R.J., Young N.D., Butler J.E., Chin K.J., Hixson K.K., Mouser P.,
RA Lipton M.S., Deboy R., Methe B.A.;
RT "Genome Sequence of the Deltaproteobacterial Strain NaphS2 and Analysis of
RT Differential Gene Expression during Anaerobic Growth on Naphthalene.";
RL PLoS ONE 5:E14072-E14072(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFK11376.1}.
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DR EMBL; ADZZ01000099; EFK11376.1; -; Genomic_DNA.
DR AlphaFoldDB; D8EYN1; -.
DR Proteomes; UP000003834; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-KW.
DR CDD; cd03364; TOPRIM_DnaG_primases; 1.
DR Gene3D; 3.40.1360.10; -; 1.
DR Gene3D; 3.90.580.10; Zinc finger, CHC2-type domain; 1.
DR InterPro; IPR036977; DNA_primase_Znf_CHC2.
DR InterPro; IPR034151; TOPRIM_DnaG_bac.
DR InterPro; IPR006171; TOPRIM_domain.
DR PANTHER; PTHR30313; DNA PRIMASE; 1.
DR PANTHER; PTHR30313:SF2; DNA PRIMASE; 1.
DR Pfam; PF13662; Toprim_4; 1.
DR SUPFAM; SSF56731; DNA primase core; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Primosome {ECO:0000256|ARBA:ARBA00022515};
KW Reference proteome {ECO:0000313|Proteomes:UP000003834};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 246..311
FT /note="Toprim"
FT /evidence="ECO:0000259|Pfam:PF13662"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFK11376.1"
FT NON_TER 340
FT /evidence="ECO:0000313|EMBL:EFK11376.1"
SQ SEQUENCE 340 AA; 38591 MW; 8CEB1AED465E0C32 CRC64;
IVTESRVKLS QVWEQASWLE VIRVFDLEVD PKRSRRDDEI WIKSPFTHEE KASMHVSLSE
NIFKDFSSGK GGGIMQFCRE MLLQKGREMT MSEVARWMVK EGIATANHPK SLVKQKEKAA
NTGTNPAIKI DLRRYLRTDH PELCRRGISA TTCRYLGCGF LPRRSWAKTG SPLNSRLVFQ
VRGVRENGQG LQPVILTHTG RALSMEQEEL NGKYWSYPFK KAWEIYNQDN ILLDEAALGQ
TNMFGLILTE GFFDVAKLVE AGCRNAVALM GNAISLGQIE RLVWIRSRVR FPRILLFLDR
DPAGKTGALQ YGKGSFTTVF PSLYLTGNSW CLSMVRNPAH
//
