ID D8F6C9_9DELT Unreviewed; 647 AA.
AC D8F6C9;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Putative CoB--CoM heterodisulfide reductase iron-sulfur subunit A {ECO:0000313|EMBL:EFK08672.1};
GN ORFNames=NPH_2202 {ECO:0000313|EMBL:EFK08672.1};
OS delta proteobacterium NaphS2.
OC Bacteria; Deltaproteobacteria.
OX NCBI_TaxID=88274 {ECO:0000313|EMBL:EFK08672.1, ECO:0000313|Proteomes:UP000003834};
RN [1] {ECO:0000313|EMBL:EFK08672.1, ECO:0000313|Proteomes:UP000003834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NaphS2 {ECO:0000313|EMBL:EFK08672.1,
RC ECO:0000313|Proteomes:UP000003834};
RX PubMed=21124915; DOI=10.1371/journal.pone.0014072;
RA Didonato R.J., Young N.D., Butler J.E., Chin K.J., Hixson K.K., Mouser P.,
RA Lipton M.S., Deboy R., Methe B.A.;
RT "Genome Sequence of the Deltaproteobacterial Strain NaphS2 and Analysis of
RT Differential Gene Expression during Anaerobic Growth on Naphthalene.";
RL PLoS ONE 5:E14072-E14072(2010).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the HdrA family.
CC {ECO:0000256|ARBA:ARBA00006561}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFK08672.1}.
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DR EMBL; ADZZ01000356; EFK08672.1; -; Genomic_DNA.
DR AlphaFoldDB; D8F6C9; -.
DR OrthoDB; 9766627at2; -.
DR Proteomes; UP000003834; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR039650; HdrA-like.
DR PANTHER; PTHR43498:SF1; COB--COM HETERODISULFIDE REDUCTASE IRON-SULFUR SUBUNIT A; 1.
DR PANTHER; PTHR43498; FERREDOXIN:COB-COM HETERODISULFIDE REDUCTASE SUBUNIT A; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000003834}.
FT DOMAIN 557..587
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 595..624
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 647 AA; 69965 MW; 8DCE31E67FDF00CA CRC64;
MADDNKDKKA TSEQKVGVYV CHCGGNISDH VAVEEVCKNA EKIPGVVKVQ NDVFMCSDPG
QELIMEDIKN GTVDRVVVAS CAPDLHSSTF RNAIQRAGGN PYIYEHANIR EQVSWVHHGD
QATNKATRLV AAAAAKAREL QPLEPFKVDA KRHVTVIGGG IAGLKSALDL ARKGLDVALI
DKSPFLGGWT AKWDRAFPTD DPVSELVTAL AGEVLNSEKI TVYTCSRITA FEGFIGNFKL
TLTQAPPESD AYEDEIKRLS DSGKGFGEFV PLAGICPAGI PETTTTHDIE TGAIVLATGF
LPYAPRYGEY RYGESKEVIT LPELIRIMAE NRQKGVGDTL EINDRKIRSV AMIHCVGSRQ
IPGIHEPDAK GNLNEYCSRT CCSATLHAAS MIRNNHPKTR VFDFYRDIRT YGRGQEELYE
EASDSKVVFF RFEADAPPEV TRNTGSGDFP LNIKVKDTLT FDEELEMPVD LVVLAVGMEP
GNISDLVEMM KLPVGVDGFL QEVHPKLRPV EIAQSGVLLA GTCQAPFDMG ETCSAASGAA
AKASAILGKG YVELDPFVAE VDLNKCLGTG TCVNACIVEG ALSLVEMDVD GEKVKRAQVN
PALCTGCGAC VAVCPENAIN VKGWTLKQYE DMVDMIVSDR ILPSQTA
//
