ID D8FD84_9DELT Unreviewed; 364 AA.
AC D8FD84;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Addiction module antidote protein, HigA family {ECO:0000313|EMBL:EFK06283.1};
GN Name=higA {ECO:0000313|EMBL:EFK06283.1};
GN ORFNames=NPH_4729 {ECO:0000313|EMBL:EFK06283.1};
OS delta proteobacterium NaphS2.
OC Bacteria; Deltaproteobacteria.
OX NCBI_TaxID=88274 {ECO:0000313|EMBL:EFK06283.1, ECO:0000313|Proteomes:UP000003834};
RN [1] {ECO:0000313|EMBL:EFK06283.1, ECO:0000313|Proteomes:UP000003834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NaphS2 {ECO:0000313|EMBL:EFK06283.1,
RC ECO:0000313|Proteomes:UP000003834};
RX PubMed=21124915; DOI=10.1371/journal.pone.0014072;
RA Didonato R.J., Young N.D., Butler J.E., Chin K.J., Hixson K.K., Mouser P.,
RA Lipton M.S., Deboy R., Methe B.A.;
RT "Genome Sequence of the Deltaproteobacterial Strain NaphS2 and Analysis of
RT Differential Gene Expression during Anaerobic Growth on Naphthalene.";
RL PLoS ONE 5:E14072-E14072(2010).
CC -!- SIMILARITY: Belongs to the short-chain fatty acyl-CoA assimilation
CC regulator (ScfR) family. {ECO:0000256|ARBA:ARBA00007227}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFK06283.1}.
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DR EMBL; ADZZ01000670; EFK06283.1; -; Genomic_DNA.
DR AlphaFoldDB; D8FD84; -.
DR OrthoDB; 9796786at2; -.
DR Proteomes; UP000003834; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010359; IrrE_HExxH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR PANTHER; PTHR43236; ANTITOXIN HIGA1; 1.
DR PANTHER; PTHR43236:SF1; BLL7220 PROTEIN; 1.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF06114; Peptidase_M78; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000003834}.
FT DOMAIN 21..75
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 364 AA; 41594 MW; 571803B9DF016462 CRC64;
MVRPAENQYL PDTVSPPGET LQETIVALGM SQAGLAERTG RSKKTINEII KGKAPITPKM
SLELERVLGV PASFWNNRER NYREALARIE EKNTLQAQVE WLKSVPVKDM IRWGWIKQFE
EKVQQLQEVL TFFGIASPDQ WPTVMASLGQ KVAFRKTEAF EVDNGALMAW LRKGEVEAKK
IECSPYSEKK FRSCLYTIRE LTVEPPEIFQ KRLTELCAGC GVVVIFVPEL PRTRVSGATR
WVTANKALIQ LSLRYKSNDH LWFSFFHEAG HIIKHGKKAI FLEGTGLGMD QDKEEEANRF
ASDFLIPRQQ YLRFVRDRSL SKFNINRFAS KLGVAPGIVV GRLQHDKHLP VTHCNDLKIK
LKWA
//
