ID D8FTZ8_9CYAN Unreviewed; 612 AA.
AC D8FTZ8;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Putative Adenylate cyclase {ECO:0000313|EMBL:CBN53838.1};
DE EC=4.6.1.1 {ECO:0000313|EMBL:CBN53838.1};
GN ORFNames=OSCI_270029 {ECO:0000313|EMBL:CBN53838.1};
OS Kamptonema sp. PCC 6506.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Microcoleaceae; Kamptonema.
OX NCBI_TaxID=272129 {ECO:0000313|EMBL:CBN53838.1, ECO:0000313|Proteomes:UP000004532};
RN [1] {ECO:0000313|Proteomes:UP000004532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6506 {ECO:0000313|Proteomes:UP000004532};
RX PubMed=20675499; DOI=10.1128/JB.00704-10;
RA Mejean A., Mazmouz R., Mann S., Calteau A., Medigue C., Ploux O.;
RT "The genome sequence of the cyanobacterium Oscillatoria sp. PCC 6506
RT reveals several gene clusters responsible for the biosynthesis of toxins
RT and secondary metabolites.";
RL J. Bacteriol. 192:5264-5265(2010).
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DR EMBL; CACA01000024; CBN53838.1; -; Genomic_DNA.
DR RefSeq; WP_007353065.1; NZ_CACA01000024.1.
DR AlphaFoldDB; D8FTZ8; -.
DR OrthoDB; 337251at2; -.
DR Proteomes; UP000004532; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR007890; CHASE2.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR Pfam; PF05226; CHASE2; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM01080; CHASE2; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:CBN53838.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004532};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 412..550
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 612 AA; 68451 MW; C35B2943F77873D0 CRC64;
MNFKDWMVHL KKTISVVQKY LASNPPWLTG AIAAVVSVGM LQLGAWRPLE YLGYKTLFQL
RDRSIIPNPG WDRRIVVIGI DDRSLQEYGQ FPWSRDRYVQ LLESLKKSAP TAIGFDILFI
DPSPKDAELA AAIKASGNVA LARTGDEENL VPEIKAAALF VGDILHESDA DGISRRANLW
FNGTPSFSSA LIQIYNIHNP GNPILLPQPI VGVEQQKVAV NWPGKTRFLT TYGFSDVVAG
KIPQDAFTNK LILVGFVAEG LDRVRTPLDR TTAGVYLHAA MIDNLLNSRL LRRVPKVWEI
ILLLGIGPVT SWILFHRDVK ERTTIAIGLP TAWFTVAALL FGFSHWWIPI ASPIGTIILA
GIALQAREQY EKQQLMRLFE KHVDPETAQM IWKRKAEIFQ QGELEPQEVT ATVLFMDIRS
FTTISEKMRP RELLTWLNTY LEAMTDCIMN RGGVVDKYIG DAIMAVFGVP FCHTEEKEIE
QDAMNAIAAC IDMHERLNEL NKHLREEGKP LIKFGIGLHT GQLVAGSVGG ARRLNYSVIG
DAVNVAARLE AMNKEVTSDS PYNLLVTERT FDCVRDRYEA QKVGSIQLRG KAETTVVYAI
LGEKQLLTKS ET
//
