ID   D8FV36_9CYAN            Unreviewed;       402 AA.
AC   D8FV36;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=3-oxoacyl-(Acyl carrier protein) synthase II {ECO:0000313|EMBL:CBN54226.1};
DE            EC=2.3.1.41 {ECO:0000313|EMBL:CBN54226.1};
GN   ORFNames=OSCI_730006 {ECO:0000313|EMBL:CBN54226.1};
OS   Kamptonema sp. PCC 6506.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Oscillatoriales; Microcoleaceae; Kamptonema.
OX   NCBI_TaxID=272129 {ECO:0000313|EMBL:CBN54226.1, ECO:0000313|Proteomes:UP000004532};
RN   [1] {ECO:0000313|Proteomes:UP000004532}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6506 {ECO:0000313|Proteomes:UP000004532};
RX   PubMed=20675499; DOI=10.1128/JB.00704-10;
RA   Mejean A., Mazmouz R., Mann S., Calteau A., Medigue C., Ploux O.;
RT   "The genome sequence of the cyanobacterium Oscillatoria sp. PCC 6506
RT   reveals several gene clusters responsible for the biosynthesis of toxins
RT   and secondary metabolites.";
RL   J. Bacteriol. 192:5264-5265(2010).
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC       synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC       ECO:0000256|RuleBase:RU003694}.
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DR   EMBL; CACA01000070; CBN54226.1; -; Genomic_DNA.
DR   RefSeq; WP_007353453.1; NZ_CACA01000070.1.
DR   AlphaFoldDB; D8FV36; -.
DR   OrthoDB; 9808669at2; -.
DR   Proteomes; UP000004532; Unassembled WGS sequence.
DR   GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR   CDD; cd00834; KAS_I_II; 1.
DR   Gene3D; 3.40.47.10; -; 1.
DR   InterPro; IPR000794; Beta-ketoacyl_synthase.
DR   InterPro; IPR018201; Ketoacyl_synth_AS.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
DR   PROSITE; PS00606; KS3_1; 1.
DR   PROSITE; PS52004; KS3_2; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000313|EMBL:CBN54226.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004532};
KW   Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:CBN54226.1}.
FT   DOMAIN          2..400
FT                   /note="Ketosynthase family 3 (KS3)"
FT                   /evidence="ECO:0000259|PROSITE:PS52004"
SQ   SEQUENCE   402 AA;  42561 MW;  3FBCF32B0F498820 CRC64;
     MSVKVVITGI GLVSALGTLE SSWNQILSGN SGIRLHQPFP EIECRPLALI GKKPVELIKL
     TRQVLADAII DADLFLPLPD CGLVIGSSRG NQAKLEQFAR EGRRKKEEKR RKKEEKFTYL
     AEDEEGKELP ITNYQFLDCL PHAGAIAAAN FIGTRGPVLA PAAACATGIW AIAQAFELIQ
     TGQCDRVIAG AVEAPITPLT LAGFNQMGAL AQTGAYPFDS QREGFVLGEG AAVLVLESAE
     LAKRRGAKIY GQVLGFGLTN DACYGTAPDL GGKSAIAAIE QCLSRSKLSV NDIDYIHAHG
     TATNLNDEHE AMLTEKLFPQ GVAISSTKGA TGHTLGASGA LGAALCLMSL KHQILPPCVG
     LRTSLFELDL VMAARGSKIG NTLCFSFGFG GQNAVIALGR YR
//