ID D8FXY3_9CYAN Unreviewed; 568 AA.
AC D8FXY3;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=OSCI_1600023 {ECO:0000313|EMBL:CBN55223.1};
OS Kamptonema sp. PCC 6506.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Microcoleaceae; Kamptonema.
OX NCBI_TaxID=272129 {ECO:0000313|EMBL:CBN55223.1, ECO:0000313|Proteomes:UP000004532};
RN [1] {ECO:0000313|Proteomes:UP000004532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6506 {ECO:0000313|Proteomes:UP000004532};
RX PubMed=20675499; DOI=10.1128/JB.00704-10;
RA Mejean A., Mazmouz R., Mann S., Calteau A., Medigue C., Ploux O.;
RT "The genome sequence of the cyanobacterium Oscillatoria sp. PCC 6506
RT reveals several gene clusters responsible for the biosynthesis of toxins
RT and secondary metabolites.";
RL J. Bacteriol. 192:5264-5265(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
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DR EMBL; CACA01000141; CBN55223.1; -; Genomic_DNA.
DR RefSeq; WP_007354446.1; NZ_CACA01000141.1.
DR AlphaFoldDB; D8FXY3; -.
DR OrthoDB; 9805821at2; -.
DR Proteomes; UP000004532; Unassembled WGS sequence.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 3.40.50.10870; Glycosyl hydrolase family 3; 1.
DR InterPro; IPR041518; Bac_GH3_C.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF18034; Bac_GH3_C; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000004532};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 8..334
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 418..567
FT /note="Bacterial Glycosyl hydrolase family 3 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18034"
FT REGION 353..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..384
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 568 AA; 60744 MW; 0C1DEB6F3297E505 CRC64;
MIENLSLAEL VAQMVVVRAS GYLFDHQIRY PEWEPPASKL RYWLENLGVG GVILVGGSAA
ELAVRSQLLQ SWAKIPLLLA ADIEEGVGQR FAGATWFPPP MAIGAVAQKD GNQAERYAEE
MGAITATEAI AIGLNWVLAP VVDVNNNPDN PVINVRAFAE TPDLVSRLAT AFIHGAQKYP
VLTTAKHFPG HGDTAVDSHL ELPTLPHSAT RLAEVELPPF IEAIAAGVDA VMSAHLIISV
WDAEWPATLS PKILTGKLRQ ELGFEGLIVT DALVMGAIAN QYGSEEAAIL AVAAGADILL
MPQDPEATIK AVCDAVAQGR IERSRIEDSV QRIWQAKAKV GLSIEYTGER VAKFSPSSPS
SPSSPSSPSS PSSPSSPSSP SSPSPLSLLP SSLTVAANIL RDSLKVGVSV PLRVEAPKNG
ENLRNLVIVD DVLGCEFLGH HTPAIAVPKQ RGYKLQIIDD RTERHKEEQF IISKNTPPHS
PEGEFVPTLL QVFIRGNCFR GSAGLTQAAG DLFKSLLNTG ELQAVVIYGS PYILEQFLPA
LPPSIPYVFS YGQMPVAQEI ALQALFGS
//
