ID D8JS02_HYPDA Unreviewed; 445 AA.
AC D8JS02;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Tol-Pal system protein TolB {ECO:0000256|HAMAP-Rule:MF_00671};
DE Flags: Precursor;
GN Name=tolB {ECO:0000256|HAMAP-Rule:MF_00671};
GN OrderedLocusNames=Hden_2423 {ECO:0000313|EMBL:ADJ24220.1};
OS Hyphomicrobium denitrificans (strain ATCC 51888 / DSM 1869 / NCIMB 11706 /
OS TK 0415).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Hyphomicrobiaceae; Hyphomicrobium.
OX NCBI_TaxID=582899 {ECO:0000313|EMBL:ADJ24220.1, ECO:0000313|Proteomes:UP000002033};
RN [1] {ECO:0000313|Proteomes:UP000002033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51888 / DSM 1869 / NCIB 11706 / TK 0415
RC {ECO:0000313|Proteomes:UP000002033};
RX PubMed=21705585; DOI=10.1128/JB.05453-11;
RG US DOE Joint Genome Institute;
RA Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL J. Bacteriol. 193:4567-4568(2011).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. {ECO:0000256|HAMAP-
CC Rule:MF_00671}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418,
CC ECO:0000256|HAMAP-Rule:MF_00671}.
CC -!- SIMILARITY: Belongs to the TolB family. {ECO:0000256|ARBA:ARBA00009820,
CC ECO:0000256|HAMAP-Rule:MF_00671}.
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DR EMBL; CP002083; ADJ24220.1; -; Genomic_DNA.
DR RefSeq; WP_013216379.1; NC_014313.1.
DR AlphaFoldDB; D8JS02; -.
DR STRING; 582899.Hden_2423; -.
DR KEGG; hdn:Hden_2423; -.
DR eggNOG; COG0823; Bacteria.
DR HOGENOM; CLU_047123_0_0_5; -.
DR OrthoDB; 9802240at2; -.
DR Proteomes; UP000002033; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR HAMAP; MF_00671; TolB; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR014167; Tol-Pal_TolB.
DR InterPro; IPR007195; TolB_N.
DR NCBIfam; TIGR02800; propeller_TolB; 1.
DR PANTHER; PTHR36842; PROTEIN TOLB HOMOLOG; 1.
DR PANTHER; PTHR36842:SF1; TOL-PAL SYSTEM PROTEIN TOLB; 1.
DR Pfam; PF07676; PD40; 3.
DR Pfam; PF04052; TolB_N; 1.
DR SUPFAM; SSF52964; TolB, N-terminal domain; 1.
DR SUPFAM; SSF69304; Tricorn protease N-terminal domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_00671};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_00671};
KW Periplasm {ECO:0000256|ARBA:ARBA00022764, ECO:0000256|HAMAP-Rule:MF_00671};
KW Reference proteome {ECO:0000313|Proteomes:UP000002033};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|HAMAP-Rule:MF_00671}.
FT DOMAIN 40..139
FT /note="TolB N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04052"
FT REGION 291..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 445 AA; 48773 MW; E016217035204FD3 CRC64;
MSPKNPLQYA LAFICLIAVG LALDSGFATR AQAQLKGTQT EGTIAPIPIA IPLFVGDDPQ
LAANVSDVLQ ADLERSGLFR PLDRASFLEQ IRDVNAVPRF GDWRSVQADA LVVGRIVNAG
DGRVGAEFRL WDVASGKQLA GQRFSTSAQN WRRIAHMIAD SVYERLTGEK GYFDTRVVFV
DETGPAQNRV KRLAIMDQDG ANVRLLTQGK ELVLTPRFSP TNQEITYMSY TSDQPKVFIM
NLESGRRELV GDFPGMTFAP RFSPDGQRVV MSLGTPDGRS SIYEMDLRTR QPRRLTESSG
IDTSPSYSPD GRQIVFESDR DGTQKLYVMN ADGSGAHPIS LGGGSYSTPV WSPRGDYIAF
TQQAGGRFLI GVMKPDGSGE RVLTEGFHNE GPTWAPNGRV LMFWRDSQST SGGPKIYSVD
ITGFNERQVT TPSFASDPAW SPLLN
//
