ID D8JYG0_HYPDA Unreviewed; 578 AA.
AC D8JYG0;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen {ECO:0000313|EMBL:ADJ23412.1};
GN OrderedLocusNames=Hden_1605 {ECO:0000313|EMBL:ADJ23412.1};
OS Hyphomicrobium denitrificans (strain ATCC 51888 / DSM 1869 / NCIMB 11706 /
OS TK 0415).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Hyphomicrobiaceae; Hyphomicrobium.
OX NCBI_TaxID=582899 {ECO:0000313|EMBL:ADJ23412.1, ECO:0000313|Proteomes:UP000002033};
RN [1] {ECO:0000313|Proteomes:UP000002033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51888 / DSM 1869 / NCIB 11706 / TK 0415
RC {ECO:0000313|Proteomes:UP000002033};
RX PubMed=21705585; DOI=10.1128/JB.05453-11;
RG US DOE Joint Genome Institute;
RA Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL J. Bacteriol. 193:4567-4568(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002083; ADJ23412.1; -; Genomic_DNA.
DR RefSeq; WP_013215571.1; NC_014313.1.
DR AlphaFoldDB; D8JYG0; -.
DR STRING; 582899.Hden_1605; -.
DR KEGG; hdn:Hden_1605; -.
DR eggNOG; COG0526; Bacteria.
DR eggNOG; COG0785; Bacteria.
DR HOGENOM; CLU_033708_0_0_5; -.
DR OrthoDB; 9811352at2; -.
DR Proteomes; UP000002033; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:InterPro.
DR CDD; cd03012; TlpA_like_DipZ_like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR003834; Cyt_c_assmbl_TM_dom.
DR InterPro; IPR013740; Redoxin.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR041017; Thioredoxin_10.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR46388; NHL REPEAT-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR46388:SF2; NHL REPEAT-CONTAINING PROTEIN 2; 1.
DR Pfam; PF02683; DsbD; 1.
DR Pfam; PF08534; Redoxin; 1.
DR Pfam; PF17991; Thioredoxin_10; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002033};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 258..403
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
SQ SEQUENCE 578 AA; 60976 MW; A5160DD691BBD6E9 CRC64;
MLLILLAYIG GILTIVSPCI LPVLPFVFSR AGQPFLRSGL PILAGMAATF ALVASLAAIG
GGWTVAANDY GRIIALIIMA VFGLTLIFPE VSERLSRPAV ALGNRLAQKA EANGEQSSPW
SSLLLGVATG LLWAPCAGPV LGLILTGAAL EGASARTTLL LAAYAAGAAT SLALALFAGG
RIFNAMKSSL GTGEWVRRGL GVAVLVAVVA IGAGADTGLL TRLSLASTAP LEQRLVDMLH
RTPGASTDSE LAAASETLPI EGRAPALTGA VDWLNSKPLT PDDLKGKVVL VDFWTYSCIN
CLRSIPYVRA WAEKYKDQGL VVVGVHSPEF AFEKNVANVR NAISDLKIAY PVAVDNNFAI
WRAFKNQYWP AHYFIDANGN IRHHHFGEGG YAASERVIQK LLAEAGKANV ADGTVSVSAS
GVEAASVFAN VASPETYVGY ARAANFVSAD GAPRDTAHTY SGEPKTLNEW SLNGNWTIAA
QHAALNTAGG SIVYRFRARD LHLVLGPSAD KKPIRFRVTI DGKEPGDSHG FDVAPDGSGT
VTEDKLYQLV RQSGDIRERT FAIEFLDPGV NAYAFTFG
//
