ID D8LCK4_ECTSI Unreviewed; 826 AA.
AC D8LCK4;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=Esi_0011_0039 {ECO:0000313|EMBL:CBN79517.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBN79517.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBN79517.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
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DR EMBL; FN647789; CBN79517.1; -; Genomic_DNA.
DR AlphaFoldDB; D8LCK4; -.
DR EnsemblProtists; CBN79517; CBN79517; Esi_0011_0039.
DR eggNOG; KOG1934; Eukaryota.
DR InParanoid; D8LCK4; -.
DR OMA; DPWMEDV; -.
DR OrthoDB; 2786103at2759; -.
DR Proteomes; UP000002630; Chromosome LG09.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR PANTHER; PTHR10796:SF92; PATCHED-RELATED, ISOFORM A; 1.
DR Pfam; PF02460; Patched; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 168..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 629..653
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 659..681
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 693..712
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 732..752
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 764..786
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 167..326
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 616..785
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 346..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..826
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 800..816
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 826 AA; 90005 MW; 8DF31964FC55975D CRC64;
MGAGRDRQGR GGGDTVQNTW GGHTYADVCA KELDGVTCAA PFRGVTRFWD GFAAYEASVT
SDADVLEAVN VEAFPDGFPV NQQTLFGNGI VYDDDGNISG VKAIIQGYAL SSDPDDDADI
NKEVFDWNEA FQDKLEASTD DFADVFEVFY LTSRSFDDAL EESVSGEIFL YFATYVIMVL
FVTVSLGRCC AGPVERRSWL GVGGIMLVVA AGLAAYGLNS GFGVPFTSLS QILPFILIGI
GVDDMFVIVA AYDHTDRALP VEERVALGVK RCGLSVTYTS LTNFFAFLLG AQSSLPAVQY
FCLYAATAIL FDFFLQMTAF VALLTMDANR QKAGKIDCCC CFTSPKHPEK QQRSQKESIQ
RGVNPRSTHR DITTDGGGGG TDGLQTRGKD DFKAEVYELS KFGRFVKETF SPCILSSTGK
AVVLLCSAWL LTSGIYGVTQ ATQGFDVLDL APDDHYARDY TAMARSYNMD ILEWYVPMRV
YTREVDYPDV AVQAEMQSTD DLLLENEFVE GPVDSWLTSF IEWAESSDTY SANVGTSGGY
VVYEDRATFY TALSAFTEDG ANARFLGDVV FNDDGTIKIS RSDMFLVGLT DTEKNVDALR
GTREVVDQSA LDPAPFAYSE VFVSSEQFVV IYGELMSSFG LALAAVFALS LLVLGKVAVV
VLVCVTLVIV DAELLGFVYL YGLDVNSITV IQLIMAVGLV VDYMVHLVHY FLHQDPRTPK
DTRIADALGE IGPSLLMGAG TTFLGIMPLV FAHNVIFRVF FKMFLVIISF GFYHGVVFVP
VMLSILPDSL ISSSPNDKRA ASVSRDDSDE HDKGGPTLLV DGTVVD
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