ID D8LD61_ECTSI Unreviewed; 1226 AA.
AC D8LD61;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Integral membrane bound transporter domain-containing protein {ECO:0000259|Pfam:PF13515};
GN ORFNames=Esi_0113_0078 {ECO:0000313|EMBL:CBN78428.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBN78428.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBN78428.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FN647822; CBN78428.1; -; Genomic_DNA.
DR AlphaFoldDB; D8LD61; -.
DR STRING; 2880.D8LD61; -.
DR EnsemblProtists; CBN78428; CBN78428; Esi_0113_0078.
DR InParanoid; D8LD61; -.
DR Proteomes; UP000002630; Chromosome LG23.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR049453; Memb_transporter_dom.
DR PANTHER; PTHR30509:SF9; INNER MEMBRANE PROTEIN YCCS; 1.
DR PANTHER; PTHR30509; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT-RELATED; 1.
DR Pfam; PF13515; FUSC_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 825..846
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 852..871
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 747..871
FT /note="Integral membrane bound transporter"
FT /evidence="ECO:0000259|Pfam:PF13515"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 427..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 499..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 903..990
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1118..1144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1226 AA; 130230 MW; 29883B141EC7A815 CRC64;
MANQGHDRRE QTSRSHGKKM PAYRPPSDFR VNVEAGLRTT LSLGLVFLWL GFGPFGGGLS
FFAGVTAIVC VGGSAGQTIS RSLMMTHGAL VGAICAILPR WLMQWGRFPA GAGFFAAVFL
VLRSRRLTSL GKKFGCVGVT LLVLGKMSDD GLTLSWWGSV ATFVRVHIEG GVTALVASLL
PYPRLATREG ALRAQFMCHS LSSAVDARVT GFIKGRDETS ISRARLLCLQ VRQNLEIIRM
ELGWSRLELG LLFGGFCAGG MQSANALEEL SELMEQVLQG VRGMRQSMVD MHRTRAQASF
SRVVGSSLRG VSKAVDVTLE ATSRRSALLP ASILACCHRY TGIPMMQPHP DDSKDVLVNT
ENKPSKHLQP AFPPSFPSPC FYFDNAGIPI FLPAPTHSKD ALGTADNTST AMKTSSVDNN
NAAAAAAAAV AGTGGPVDDD EERGLRSSTE PPPLRRQSSL LETTGRLEEA VSRMMKDYQR
ARKEVLYGLD DLGRPLEEVA SSGREVDSGG RSPSLPRDPV SLEDLQSLSK RINLPRTGSI
NLSGLKNGLS TTAGGLPARS KEAEVSEGIG GRRREGDPLG GVPNHVLVMK ERQKLGSAAT
MARGAFLFSL SGLCSALTKK RVNRTGGWRP SQSAEAARFV FSGLWTAIRP PPGLLGALSS
TPGFLAARCF RRRDSSRGHR RKAKSALKRL GAGSGPGSPT PRPGGVREGG CLSAVTRSGY
FWCFKVSLAL TLCAVFSLSP FLAELFEPSV WISVTASFVM DTQSASAVST SLLRLVGTVL
GAVYGILAAK LAGQPEDESY SFQTYAILLP WVAVTCFFRN SSQFSYAALV AAFTAVVIFT
SSNTVLGANG EAVSLARIVN TVVGSVVYLL VDMLLAPTRA KNLVLEQIYL SLDAAFREPG
FLDGGGSGRP LDPTPIVSGE QGRDSPPGKP AAGSPPAESA GPAGSPAGGE DGPLRDEGRR
IVDVPRGSGL AGVRWEGSGA EEGEGSRLEG EAAATAAVVS TTSWGGREKE PGGIRKMVCA
LALQKRYLPL AELEPQLWYE AFPASAYQDM VAAQEELLRA LTLLTKSAIA VSEDRSTEWR
RELSELGSHL ASLVQLLKIA LEDARDVFGG GDLPKAFSHR GGGGDADADS DSDGGGGGGG
EEGEGMLRML DVQADAMRLN ADVQSDFVMF IQAFMDRGAF PVWELESILR ISTAVLAVMG
VQRALLTLGH AVATVVDRES YGSYYR
//
