ID D8LFQ0_ECTSI Unreviewed; 882 AA.
AC D8LFQ0;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=TrkA-C domain protein {ECO:0000313|EMBL:CBN75624.1};
GN ORFNames=Esi_0151_0006 {ECO:0000313|EMBL:CBN75624.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBN75624.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBN75624.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FN648075; CBN75624.1; -; Genomic_DNA.
DR AlphaFoldDB; D8LFQ0; -.
DR STRING; 2880.D8LFQ0; -.
DR EnsemblProtists; CBN75624; CBN75624; Esi_0151_0006.
DR eggNOG; KOG1281; Eukaryota.
DR InParanoid; D8LFQ0; -.
DR OrthoDB; 1359392at2759; -.
DR Proteomes; UP000002630; Unplaced LGUn.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR InterPro; IPR031312; Na/sul_symport_CS.
DR PANTHER; PTHR43652; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR PANTHER; PTHR43652:SF2; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR Pfam; PF03600; CitMHS; 1.
DR PROSITE; PS01271; NA_SULFATE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 691..709
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 715..732
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 744..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 782..809
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 821..840
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 860..880
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..811
FT /note="Citrate transporter-like"
FT /evidence="ECO:0000259|Pfam:PF03600"
FT REGION 360..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 534..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 584..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..380
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 882 AA; 93788 MW; 79C3CC851DE1358D CRC64;
MADSSDSSGS PAEAAFMGVV LTVMFISLFV GLKTPETVVF FCLVLVWNVG LVNTTEALSG
FSNAGMLAVG ALFVVIKGVE KSQLADKAAR RVFGLRTSLE AGLGRMMSLC FVLSAFLNNT
PVVALLIPIT RDWARARGFS PSIFLIPLSY SCIMGGLLTV IGTSTNLVVQ GLVLDEKLSD
PSIEAIGFFE PGYIGVPLGV VGMLYLVLFA PRVLPSRGGL FRYVRDRAKE LLTEVQVMDD
FPYKGEPAGL VLARLGLPQD TLIKIRRKIS SGILRQMSQS LGENASLGFS TSALYSSSVK
EGATHDEQDV NAIMEVNQKT FRAESMYSYR MRAECLWGTK DDLAQEEKCI SPLAGTAVED
VSGSEARKPG RFSRKRWVSD ADAQRSSNAI AAVNGNNATP NGNASATAAG NVAAGQGQPN
GGSLNAAGET YTDIFPVSPA EPVQAGDVLF LSCAQAREEA TMIDFQAVTV SQGLKGLKFL
DVSALDLPGH GTEFFEIVLS GHNHFVGRSA SRDNAEFAAY YNVSVVAVRR RGQAEASNPG
SSVAAAPPSD STRPTGSSFK SSRAAAAAAM DAPEVFLEEG VEPALNPDSR EVSPTGSIST
SAGPKTRSLV SAMSGRAAAA ASRGTPRSPM MRRSRKNTLI HEDEKDVTET SFKAGDVVLV
LAKEEFMEKY GSSRDFFLLT KVGSVPKPVR YYDYLPLLAF VGMLVWVLLD AEMVQAAFTA
GAILIFGGWV DAKKTVGFVD WSLLLLIGSA LGLSKGIVNS GLADYVGGAI RSSGISADAS
LFVLYGFTMI FTELITNNAA AALATPIAFS ISRELEVSYK PFILTVMLAA SSSFITPIGY
QTNTLVWGPG GYKFTDFMKI GTPLSLIYLV LGSLLVPQIF PF
//
