ID D8LN03_ECTSI Unreviewed; 696 AA.
AC D8LN03;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Dynein heavy chain {ECO:0000313|EMBL:CBN76244.1};
GN Name=DYHC16 {ECO:0000313|EMBL:CBN76244.1};
GN ORFNames=Esi_0421_0017 {ECO:0000313|EMBL:CBN76244.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBN76244.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBN76244.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
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DR EMBL; FN648621; CBN76244.1; -; Genomic_DNA.
DR AlphaFoldDB; D8LN03; -.
DR STRING; 2880.D8LN03; -.
DR EnsemblProtists; CBN76244; CBN76244; Esi_0421_0017.
DR InParanoid; D8LN03; -.
DR OrthoDB; 312195at2759; -.
DR Proteomes; UP000002630; Chromosome LG03.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR PANTHER; PTHR10676:SF352; CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF08385; DHC_N1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002630}.
FT DOMAIN 263..677
FT /note="Dynein heavy chain tail"
FT /evidence="ECO:0000259|Pfam:PF08385"
FT REGION 90..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..225
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 696 AA; 76889 MW; CF815285E16CED0C CRC64;
MMKTAPYSRP VGGKKQCLAV LLDPQPVNSS KAWKQPKSCA SAFTLLQKST RDEILRAVQG
RKELQLFLDD PNTAVLCVRA HPGGDLRLDN GLELLDGGSE RETKEGGDED ESPAEGRVGL
HFVKLRPEPV TGGNIRSLVQ VSSMTGSPLN SLYHSVHSVY APALLKNEAG RQELSGKVQS
VIALLDSTLG DAVIYGGGGD ISHDNDNSSH NNNSNEDRKG NTSRQNGNLS CFGGIVYPSD
EFQFWSGYSG RAADRELVTA VARALEPLRE PFAALSGLQT EELEELMDIT HTALDEVWKA
DGGGGARGSY PQARMAHLFD VIGAALCRHV QEKLRPLDIW AGPLSDVRTR LLEGAQICSK
WCRITEELSS SYWSGFIQHP WKGDPHVDNL TAGTAARLEE IHRLRTTREE LGRLLGRGRG
GGMADDSHEI FKPFREMSAL SYNPYTQQEW ESRVKDFEKS LQPLETAAAN SFRRRIGGMN
ARPQLLLKEF QRFANLMRRR QIREALGSER EALLSQLTEQ MAELEAAFDE QDLSSGVHGH
HPSAAGDTLP WGRNLSPRIR GVVYCRQLCA RVRATGEAAS SVLSDLSSFR AFEEISSELV
RKTRRREASL FEEWQEEVQD GLDGGELSTQ MRGKLMDIDK RGILVVNYSE RLVTLLREVR
QLSELGHAIP SKISKTVLPS GQAVFFFAAS LGSIML
//
