ID D8LN57_ECTSI Unreviewed; 1154 AA.
AC D8LN57;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=Thioredoxin domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=Esi_0043_0092 {ECO:0000313|EMBL:CBN74820.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBN74820.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBN74820.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
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DR EMBL; FN648630; CBN74820.1; -; Genomic_DNA.
DR AlphaFoldDB; D8LN57; -.
DR STRING; 2880.D8LN57; -.
DR EnsemblProtists; CBN74820; CBN74820; Esi_0043_0092.
DR eggNOG; KOG0910; Eukaryota.
DR InParanoid; D8LN57; -.
DR OrthoDB; 37308at2759; -.
DR Proteomes; UP000002630; Chromosome LG03.
DR CDD; cd09212; PUB; 1.
DR CDD; cd02947; TRX_family; 1.
DR CDD; cd14291; UBA1_NUB1_like; 1.
DR Gene3D; 1.20.58.2190; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR036339; PUB-like_dom_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR017937; Thioredoxin_CS.
DR InterPro; IPR013766; Thioredoxin_domain.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45663; GEO12009P1; 1.
DR PANTHER; PTHR45663:SF11; GEO12009P1; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR Pfam; PF00627; UBA; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF143503; PUG domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00194; THIOREDOXIN_1; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
DR PROSITE; PS50030; UBA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..1154
FT /note="Thioredoxin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003117315"
FT DOMAIN 353..392
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 398..438
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 506..629
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT REGION 25..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 88..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 130..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 795..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 986..1113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 383..410
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 27..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..208
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 477..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 799..816
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 986..1006
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1007..1039
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1061..1076
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1154 AA; 120787 MW; 7074596FCEA76C24 CRC64;
MLMILRTAMA AAALLAAVDQ ASGFVSTRRR HHGSSSSPGT RHSYNGGDGL ASGGAPLTST
TVDHLTLSRE SPYPFESSAA RTVRGLVATQ RSKRSNRGGG NGATVQPRPG METQLGGWSY
ARTVLTNLSK GAGREGESGT DESGDAAAAA GGSAQSSSGG SSGGKGADGA PAKGNKGAGG
GGAGLGIGGG GGDGDDDDDD EEEEEKKGKE AGDEDGLDSW DLSEFGDSQD GLGIEFSEAG
VGEDEEQQEG ENGGLSGAKA AVDGGDDAQA GQEQGGALPQ EYEVVCDGDV CERRPVGPNP
AQTVPAVDGA AAEAGAATGA ASAGAAASSG ADNALVPDAG GDSDGGGGVP PSAVDPGVAQ
LVSMGWEAEE STAALEASGG DVVAAAEALA AQEEEDLERY EEGLADLQQR GWDSDVAMSA
MREAGGNSTA ALHALEEEDR VLSMQFEQSI EEMVEHGWDE EVARKALLMQ WQKDIEGKGG
SRKDQKQFEK TVQGVHQKGV KEGKASTTKK SEPPAPTPAK REDVVFEVTD KTLQKVVLES
PVPVILDVYA EWCGPCKQLT PALEEAAMRS GGMFRVAKVD AEKQRSIAEV LGIHAFPSVF
GMKDGIILDN FVGGLAQDEM QSFMMGVVMG MPPPKDQALR EHQKSQAELR GISRKLAHVA
GLAVLGSRKK ESLCLKVDKA LGETLEGELP EGGGPAAENA PAVAAAKKAA RTVITVLMSA
YKFPEDPKYR TLSTTSKAYE EVLAPHPPML EALRLAGFRH KDGDESHLTL LHRNMAVLAS
VQDRVEVWNK GIKMPQIEED SEDEYDDSED EEDEEELERI KQARERLATV AKLEITDSSG
GHEAVVKLTM EADSTLGELF RTLQEEEGFG ADLVLKTAFP KRELAASDES CHSSTLLSLG
LAPSARLVAT TAAALAAEQE AEGGDAEAAA VRKEELRAKM MEKARDGKRK GIKKAGTLFG
ADDGIIEVKK GKHQEYFGGD STVTLAAEDS DDEDGDEGDG SDNQEAASQE DDFGQSGGEP
SLSDDQENDN GSSYSSSENE EGEGGEEQMT DASRNDDNGE EDYSPESEEE SDLSDERFSE
GDTGTSATES EGTRTDFDAD EASYASGVGG EEHRWGELAK LLVQSHGRRE CFGALLRDSS
PPFFGSSTGW LSVR
//
