ID D8LRP2_ECTSI Unreviewed; 1295 AA.
AC D8LRP2;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
GN ORFNames=Esi_0069_0081 {ECO:0000313|EMBL:CBN77803.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBN77803.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBN77803.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR005719}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC1 subfamily.
CC {ECO:0000256|ARBA:ARBA00005597}.
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DR EMBL; FN648916; CBN77803.1; -; Genomic_DNA.
DR STRING; 2880.D8LRP2; -.
DR EnsemblProtists; CBN77803; CBN77803; Esi_0069_0081.
DR eggNOG; KOG0018; Eukaryota.
DR InParanoid; D8LRP2; -.
DR OMA; SYIRDHT; -.
DR OrthoDB; 231904at2759; -.
DR Proteomes; UP000002630; Chromosome LG26.
DR GO; GO:0008278; C:cohesin complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd03275; ABC_SMC1_euk; 1.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR028468; Smc1_ABC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR18937:SF12; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN; 1.
DR PANTHER; PTHR18937; STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005719};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630}.
FT DOMAIN 527..644
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT REGION 354..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 962..1045
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 171..300
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 485..512
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 821..885
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 924..951
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 385..419
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1004..1037
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1295 AA; 144456 MW; 956C10EBD64C22A5 CRC64;
MGRLIRIEAE NFKSYAGTQI IGPFKDFTAV IGPNGAGKSN LMDAISFVLG VQSKHLRSTK
LSDLVFRADG AVPSSRRAMV KVVYMVGEGE EVGGQEAGDE VHFSRVISAG GASSYRLNDK
EVTWESYEKR LRSIGVLVKA RNFLVFQGDV ESIASKSPKE LTQLFEQISG SDESKAEYEE
LKAAKEKAEE DTIFSFKRKK GCQAERKQVK EQKEEAERFQ KKLKEMEDLK IESFLVQLFH
INKDVDEREE DIKLMREELE EAQEREKAAD VILKSKKKEM ARLNRELQKA QAELNQQKRL
RDDMGPQHIK IKGGISTLKR QVADGDKALE KIGRDRDAQR GTVAALSRDI AAVKQREEAA
VSDGKGKGKK GGGGSSGGLA RLSEAKAAEY EKLKADARER GSGEREEMAD VERQLTNSRS
KVDQLRSEQA SLDERLSGFD ASAKRFRQRR SDMEKTTKKA ALDRAELQSQ LDELTGRSKG
DALRATEIDE ALRSINEQLR DAKDDRRMTK QQEKMADCLE TLKRIYPGVR GRLVDLCKPT
QRKFNVAVTT AAGRYMEAIV VDTKAECLEC LSYMQTNKVG RAQFIPLDTI KVKPISESLR
SLGPSHRLCA DIMQGGDDGV RKAILFAVGN TIVSDTLDAA RDLCFGSGED KKIKAVTLNG
FLISKSGNMT GGTTTRDLAR AGQWDEKEFS ELKQRRQELE GERETLSREH RNRSLKARPT
TELETKIRGL ANREKHSSAD LDITREELKS IGKHQEAAEI DRAKVNAELG EREADVSRLE
ASLLSLQNKV DAVENEVFAP FLKSVGASDI RSFEEGQLKD MQEQYKARMK LQQHRSKLEA
QLAHERSRDF DGPLDKLTRK INARRKELED QHVKMEELVE REKSIMEAED EAAKEHLAAK
EVARRHEGEV KAAHSGRQKL VKERDGISKR IMSEESALEQ LRAKLHGVLQ EARVEQVALP
LVGGGTLAGG GEGEKTRSRK RSRGEDGDEE EEEEEEHSEE NSSMEGGARS SGASGMSLSG
VSGTQGSSTA HFSQAQNASV KEDREKALEV DLSKLKKHRG AKDAQGLEEV VSGYRKQMQE
LQAQINQMTP NMRAVERFGD VSDRLKASGQ TFEQSKQNAA GAVLKFNEVK QRRYDTFMQA
YNLVSDNLNT IYKDLTRSSK HPLGGNAFLS LDNPEEPYLG GVKFNAMPPM KRFRDMEQLS
GGEKTVAALG LLFAIHSFRP APFFVMDEID AALDNINVKK VCNYIQGRSG DFQSIVISLK
DMFYEKADAL VGICRDHATN SSRTLTLDLE AVGEA
//
