ID D8LTB3_ECTSI Unreviewed; 838 AA.
AC D8LTB3;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Trypsin-like serine protease {ECO:0000313|EMBL:CBN77984.1};
GN ORFNames=Esi_0081_0086 {ECO:0000313|EMBL:CBN77984.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBN77984.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBN77984.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FN649047; CBN77984.1; -; Genomic_DNA.
DR AlphaFoldDB; D8LTB3; -.
DR STRING; 2880.D8LTB3; -.
DR MEROPS; S01.A08; -.
DR EnsemblProtists; CBN77984; CBN77984; Esi_0081_0086.
DR eggNOG; KOG1320; Eukaryota.
DR InParanoid; D8LTB3; -.
DR OrthoDB; 2159919at2759; -.
DR Proteomes; UP000002630; Chromosome LG26.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:CBN77984.1};
KW Protease {ECO:0000313|EMBL:CBN77984.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630}.
FT REGION 99..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 295..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 602..681
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..156
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..457
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..543
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 838 AA; 86718 MW; 1FAA0AD28576D250 CRC64;
MNHRRKNREI NTATAVASLL GLALSRSTAE ALRPAFVGSG SNAPHGAAKA ASGAAGSVQH
HCSLLPARRG GSIARAARPY GNREYARILR LRAAGYGAAF GQGDGKEKED EEEKEEEDVA
AKSKRLLQRA AAAVRTADQG QQRDQGEQEG ERMRKRDVFR RRRRRANAKI QAVPVLDSSC
EQTAGGGSAE APILNFGQRG RSRNSSSGAC SSGAAVDVAA AGGGHGSSKI EPKKDRRRWG
PAAVGSAVFV TPVRFVRRKV DDCRSFVVSR ERVHWASLAM ASYIFATSVL PRLPAGTSTG
GSTAGKGRSY GGYNYHDDDG EDSTLPSPEL HPYDDSPAMT SRRRGGYRQR ADYYHDDGGG
IGTTITHLDD HAEQLWHNSP AIRAAAAAAA AAAAEAAGDS LDREAGPSTR VGAPLPSRGA
AASEREAWEE DPGKEEQHRV PREPFDGSGE REGLFSDGDG LDGGSLAVDD NGVGVDPDLR
THFDLGDLEL AAEKALDLLR DSGDISGGDG GDGATEPEAD IDESGPELRP DLEDLELAAE
KALDLLRDGG GGARGQDSAG RQDDGGTSAA AAAASVTGRS TRVPVRLSVG VDTENAAAVP
AHGGAAPLSA DSSQQDANRQ QEQKEEEGKS SSSTGVAVVG GKEKTSGGRL TLPSPPAPAP
KVPPAPAIGG SGGGGGTPGR HSTSFVAVAA RAVSPAVCRI DMERLVGTRH DGSPFTDVET
GQGSGLIFSS EDGLVLTNAH VVAGARKVTV TLTDGRKFLA EVKGSDALSD LAVLKIDRDA
SLGQTPLPEV TLGDSQELQV GDWVIAVGNP VGLDSTVTLG IVSRAGLTRK ASSARHPS
//
