ID D8LXR8_BLAHO Unreviewed; 452 AA.
AC D8LXR8;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Ornithine decarboxylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=GSBLH_T00000720001 {ECO:0000313|EMBL:CBK20373.2};
OS Blastocystis hominis.
OC Eukaryota; Sar; Stramenopiles; Bigyra; Opalozoa; Opalinata; Blastocystidae;
OC Blastocystis.
OX NCBI_TaxID=12968 {ECO:0000313|EMBL:CBK20373.2};
RN [1] {ECO:0000313|EMBL:CBK20373.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Singapore isolate B {ECO:0000313|EMBL:CBK20373.2};
RA Wincker P.;
RT "Sequencing and annotation of the Blastocystis hominis genome.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-II family.
CC {ECO:0000256|ARBA:ARBA00008872, ECO:0000256|RuleBase:RU003737}.
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DR EMBL; FN668639; CBK20373.2; -; Genomic_DNA.
DR RefSeq; XP_012894421.1; XM_013038967.1.
DR AlphaFoldDB; D8LXR8; -.
DR EnsemblProtists; CBK20373; CBK20373; GSBLH_T00000720001.
DR GeneID; 24918014; -.
DR InParanoid; D8LXR8; -.
DR OMA; SFFVCDL; -.
DR OrthoDB; 48358at2759; -.
DR Proteomes; UP000008312; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0006596; P:polyamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR022643; De-COase2_C.
DR InterPro; IPR022644; De-COase2_N.
DR InterPro; IPR000183; Orn/DAP/Arg_de-COase.
DR InterPro; IPR002433; Orn_de-COase.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR11482; ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE; 1.
DR PANTHER; PTHR11482:SF6; ORNITHINE DECARBOXYLASE 1-RELATED; 1.
DR Pfam; PF02784; Orn_Arg_deC_N; 1.
DR Pfam; PF00278; Orn_DAP_Arg_deC; 1.
DR PRINTS; PR01179; ODADCRBXLASE.
DR PRINTS; PR01182; ORNDCRBXLASE.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008312}.
FT DOMAIN 90..332
FT /note="Orn/DAP/Arg decarboxylase 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02784"
FT DOMAIN 333..422
FT /note="Orn/DAP/Arg decarboxylase 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00278"
SQ SEQUENCE 452 AA; 50413 MW; 8247B877DE3D1B23 CRC64;
MLYNWSCPDT GSSYRDITII HSLIAEMSDR SGLAAVEDLN TVLNTTLDEF VERHPEVLII
DDSTTLEEFV KQYVQDHPSD KSVCIFDLTS VLVQYKTWFN VFGDVQPFYA MKCNPNPKLM
DLMCSLPGMC VDCAGVEEIN MCLSRGIKPD HIIFANPIKS VEGIECMRKN GIWTGTVDSI
EEVQKMHDVL GEDAKHCRIV IRLWVDDSHS IIALGSKFGC HLSEVRGILN QVQLCGMEAV
GVAFHVGTGN EDQYAYEKAV RDSAEVFKMA KEFGFTMTLL DLGGGWAGDL GNDKFENPSL
TSVCGIIRDA VKKHEVFSTE GFRMISEPGR YFNNNTVSVA CKVLNVSKRG GRTVYKINEG
VMGVFHDLIL CDMNFDVEPL VEGEKHPASI IGSSIMQKDV VLSNIDLPEM KVGDIILFKN
IGAYSVSLTT LPLRRNQDHV YIVRRSSLCQ HK
//
