ID   D8M4U7_BLAHO            Unreviewed;       310 AA.
AC   D8M4U7;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=LIM zinc-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=GSBLH_T00003018001 {ECO:0000313|EMBL:CBK23086.2};
OS   Blastocystis hominis.
OC   Eukaryota; Sar; Stramenopiles; Bigyra; Opalozoa; Opalinata; Blastocystidae;
OC   Blastocystis.
OX   NCBI_TaxID=12968 {ECO:0000313|EMBL:CBK23086.2};
RN   [1] {ECO:0000313|EMBL:CBK23086.2}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Singapore isolate B {ECO:0000313|EMBL:CBK23086.2};
RA   Wincker P.;
RT   "Sequencing and annotation of the Blastocystis hominis genome.";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FN668654; CBK23086.2; -; Genomic_DNA.
DR   RefSeq; XP_012897134.1; XM_013041680.1.
DR   AlphaFoldDB; D8M4U7; -.
DR   EnsemblProtists; CBK23086; CBK23086; GSBLH_T00003018001.
DR   GeneID; 24920142; -.
DR   InParanoid; D8M4U7; -.
DR   OMA; WIARVTH; -.
DR   OrthoDB; 52417at2759; -.
DR   Proteomes; UP000008312; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd00014; CH_SF; 1.
DR   CDD; cd09401; LIM_TLP_like; 2.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   Gene3D; 2.10.110.10; Cysteine Rich Protein; 2.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   InterPro; IPR001781; Znf_LIM.
DR   PANTHER; PTHR46074; CYSTEINE-RICH PROTEIN CRIP FAMILY MEMBER; 1.
DR   PANTHER; PTHR46074:SF5; LIM DOMAIN-CONTAINING PROTEIN C; 1.
DR   Pfam; PF00307; CH; 1.
DR   Pfam; PF00412; LIM; 2.
DR   SMART; SM00033; CH; 1.
DR   SMART; SM00132; LIM; 2.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 4.
DR   PROSITE; PS50021; CH; 1.
DR   PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR   PROSITE; PS50023; LIM_DOMAIN_2; 2.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE   4: Predicted;
KW   LIM domain {ECO:0000256|PROSITE-ProRule:PRU00125};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008312};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT   DOMAIN          1..107
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          142..202
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50023"
FT   DOMAIN          243..303
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50023"
SQ   SEQUENCE   310 AA;  35229 MW;  DF31CEA7FCC7CA3C CRC64;
     MQEVMGEQFP DDEEEFQNAL RNGEVICRLA NIIRPGSVRK VSLRFFFESQ INHGAVFLER
     ENVSAFISFA RSIGCPEMDL FCVNDLYELK NFKKVCMCIL SVGRYSASVE EFEGPYFIGG
     KMTYNRQGEV ERVVLDTTSE NPICPTCHKP VMFTERFTAL GEVYHKLCFK CLNCGNIIGG
     GDYCDHNNKP LCPKCYEQLY GTRPNKAEYS AKGSYRVEEN ERHTPVLSKN AEAMRDLFKP
     TVVKCATCGK TVYPAEMVTF HGQSYHKLCF VCVQCGHSIA QGEQFERDDK PYCKACYKKL
     PAFKLEAPAN
//