ID D8M6P7_BLAHO Unreviewed; 601 AA.
AC D8M6P7;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=Eukaryotic peptide chain release factor GTP-binding subunit {ECO:0000256|ARBA:ARBA00015765};
DE AltName: Full=ERF2 {ECO:0000256|ARBA:ARBA00030845};
DE AltName: Full=Polypeptide release factor 3 {ECO:0000256|ARBA:ARBA00029585};
DE AltName: Full=Translation release factor 3 {ECO:0000256|ARBA:ARBA00030210};
GN ORFNames=GSBLH_T00003341001 {ECO:0000313|EMBL:CBK23465.2};
OS Blastocystis hominis.
OC Eukaryota; Sar; Stramenopiles; Bigyra; Opalozoa; Opalinata; Blastocystidae;
OC Blastocystis.
OX NCBI_TaxID=12968 {ECO:0000313|EMBL:CBK23465.2};
RN [1] {ECO:0000313|EMBL:CBK23465.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Singapore isolate B {ECO:0000313|EMBL:CBK23465.2};
RA Wincker P.;
RT "Sequencing and annotation of the Blastocystis hominis genome.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
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DR EMBL; FN668661; CBK23465.2; -; Genomic_DNA.
DR RefSeq; XP_012897513.1; XM_013042059.1.
DR AlphaFoldDB; D8M6P7; -.
DR EnsemblProtists; CBK23465; CBK23465; GSBLH_T00003341001.
DR GeneID; 24920445; -.
DR InParanoid; D8M6P7; -.
DR OMA; ARFDECT; -.
DR OrthoDB; 5477300at2759; -.
DR Proteomes; UP000008312; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03704; eRF3_C_III; 1.
DR CDD; cd04089; eRF3_II; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR PANTHER; PTHR23115:SF36; TR-TYPE G DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008312}.
FT DOMAIN 173..405
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 72..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..99
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 601 AA; 65412 MW; F43DDFA263C112C2 CRC64;
MSFGNWSSNA KDFTPSWGNF GDDSGSGDFV PSFIKAPVPQ QPSITNQFAK KKPITLASLG
VSNQNLGGAK SVALGKSATP APAPTPAPTP APAPAPTSAP VSVAAPAAPA AQAAPSTSSL
PTAPKTEKTA SEDVTSPESE CLDVDSPEVA TETEPSTTAS FSLDELIAKE DPRENINVVF
IGHVDAGKST ICGNIMFTTG MVDKRTIEKF EREAKLRNRE SWFLAYIMDT NDEERAKGIT
VEVGRAYFET EHKRFTVLDA PGHKNYVPNM IAGAAQADAG VLVISARKGE FESGFERSGQ
TREHVLLAKT LGVKRLIVAV NKMDEETVKW SERRYNDIVT KLSPYLKRVG YNVQEDVTFL
PVSGLRGYNL KEGIPEGMCP WYSGPSLFQI LDSMQIEGRD ASAPLRLPVL DKFNDRGCVI
TGKVESGRLI VGNSVLLMPN SRKAEVQSIT INDKEVLSAK PGENVNVRLK GISDSNVFRG
DIICHEDLHI HAVKEFEARL VLLELLENRR IMTAGYGAVL HIHTAVEEVM ITDLIAEQDR
KTKAIKKHPR FVKSDSIVFA KLSLSKPVCM EMFDSMPQLG RFTIRDEGKT IAIGKVTKII
N
//
