ID D8M8B3_BLAHO Unreviewed; 411 AA.
AC D8M8B3;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Tr-type G domain-containing protein {ECO:0000259|PROSITE:PS51722};
GN ORFNames=GSBLH_T00004056001 {ECO:0000313|EMBL:CBK24302.2};
OS Blastocystis hominis.
OC Eukaryota; Sar; Stramenopiles; Bigyra; Opalozoa; Opalinata; Blastocystidae;
OC Blastocystis.
OX NCBI_TaxID=12968 {ECO:0000313|EMBL:CBK24302.2};
RN [1] {ECO:0000313|EMBL:CBK24302.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Singapore isolate B {ECO:0000313|EMBL:CBK24302.2};
RA Wincker P.;
RT "Sequencing and annotation of the Blastocystis hominis genome.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
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DR EMBL; FN668683; CBK24302.2; -; Genomic_DNA.
DR RefSeq; XP_012898350.1; XM_013042896.1.
DR AlphaFoldDB; D8M8B3; -.
DR EnsemblProtists; CBK24302; CBK24302; GSBLH_T00004056001.
DR GeneID; 24921102; -.
DR InParanoid; D8M8B3; -.
DR OMA; VACTFES; -.
DR OrthoDB; 5477300at2759; -.
DR Proteomes; UP000008312; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03705; EF1_alpha_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR PANTHER; PTHR23115:SF170; ELONGATION FACTOR 1-ALPHA 2; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008312}.
FT DOMAIN 13..240
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 411 AA; 45678 MW; FA371D9A364975AC CRC64;
MESNLFCSMG KEKPHINLVV IGHVDSGKST TTGHLIYACG GIDKRTIERF EKEANEIGKG
SFKYAWVLDK MKAERERGIT IDISLWKFQT EKYFFTIIDA PGHRDFIKNM ITGTSQADVA
ILIIAAGTGE FEAGYGKNGQ TREHALLANT LGVKQMICCV NKMDDKSVNY SEARYKEIKA
EMTSFLTKVG YQKVEERIPF IPISGFNGDN MLERSANMPW YKGPTLIEAL DNIHPPKRPP
GMTVTFAPVG VTTEVKSVEM HHESIPQALP GDNVGFNVKN VSVKDIHRGN VCGDAKNDPP
CRVDSFTAQV IVMNHPSGIR PGYCPVMDCH TAHIACKFEK IMSEMDKRTG KVLRENPDIV
KNGKSMMAEL VPSKPLCVES FQDYPPLGRF AVRDMRQTVA VGIIKSTVRA K
//
