ID D8MMM2_ERWBE Unreviewed; 566 AA.
AC D8MMM2;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Alanine/aspartate exchanger {ECO:0000313|EMBL:CAX58079.1};
GN OrderedLocusNames=EbC_05480 {ECO:0000313|EMBL:CAX58079.1};
OS Erwinia billingiae (strain Eb661).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=634500 {ECO:0000313|Proteomes:UP000008793};
RN [1] {ECO:0000313|EMBL:CAX58079.1, ECO:0000313|Proteomes:UP000008793}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Eb661 {ECO:0000313|EMBL:CAX58079.1,
RC ECO:0000313|Proteomes:UP000008793};
RX PubMed=20565991; DOI=10.1186/1471-2164-11-393;
RA Kube M., Migdoll A.M., Gehring I., Heitmann K., Mayer Y., Kuhl H.,
RA Knaust F., Geider K., Reinhardt R.;
RT "Genome comparison of the epiphytic bacteria Erwinia billingiae and E.
RT tasmaniensis with the pear pathogen E. pyrifoliae.";
RL BMC Genomics 11:393-393(2010).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC {ECO:0000256|ARBA:ARBA00009854}.
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DR EMBL; FP236843; CAX58079.1; -; Genomic_DNA.
DR RefSeq; WP_013200584.1; NC_014306.1.
DR AlphaFoldDB; D8MMM2; -.
DR STRING; 634500.EbC_05480; -.
DR KEGG; ebi:EbC_05480; -.
DR eggNOG; COG2985; Bacteria.
DR HOGENOM; CLU_035023_2_2_6; -.
DR Proteomes; UP000008793; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR InterPro; IPR022457; Asp_Ala_antiprt.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR006512; YidE_YbjL.
DR NCBIfam; TIGR03802; Asp_Ala_antiprt; 1.
DR NCBIfam; TIGR01625; YidE_YbjL_dupl; 1.
DR PANTHER; PTHR30445:SF8; TRANSPORT PROTEIN YBJL-RELATED; 1.
DR PANTHER; PTHR30445; UNCHARACTERIZED; 1.
DR Pfam; PF06826; Asp-Al_Ex; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008793};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 290..374
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 566 AA; 58798 MW; 420BD1B8A968463B CRC64;
MSGTLFPFIT QALQSVPGLA IFLALTFGYA IGQIRLGPIQ LGGVCGTLIA ALLIGQLNIP
VDTGIKNIFF MMFIFALGYS GGPQFFANLN AKGIRLGVFC LIEVVAVLAL VLTATAVMHL
DPGTAAGMMA GAATESAVVG TATDAISRLD LPASDILRLQ GNVVTAYSIT YICGLITIVI
VTSQLFPLFL RVNLREEADK LWLEMGGRVE TDGQSAAPTI VGRGYRVDAG AGYTVAAIQQ
RLGQQSSIVR VQRHGRLLAL TPELKLRRDD RVLLVGYRGS LIETAAMLGQ EMPDTTSMAA
ALETYHVVLL APAMANRPLQ EVTLPAGLHV AAIQRGDAIM PALPATRLQL HDILQIYDTT
PGGGRSSGAQ LSHIGKRMPD KLASNLGIAG LAIALGTLLG SFSLNIGGIP FSAGTGGGVL
VVGLVLGWYH ARRADLHTVN ADALALMKDL GLAGFIAGVG LSSGPQAMAL IMQYGFSLPL
LGIAIAVIPA SLSLLVGHFW LKLSAPVLLG AIAGQQCSTP ALSAIQSACG NSTPLLGYTI
TYAISNVVLP LMGPLIVGLA SSLQPV
//
