ID D8MVY1_ERWBE Unreviewed; 434 AA.
AC D8MVY1;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Alpha-ketoglutarate permease {ECO:0000313|EMBL:CAX60988.1};
GN Name=kgtP {ECO:0000313|EMBL:CAX60988.1};
GN OrderedLocusNames=EbC_34570 {ECO:0000313|EMBL:CAX60988.1};
OS Erwinia billingiae (strain Eb661).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=634500 {ECO:0000313|Proteomes:UP000008793};
RN [1] {ECO:0000313|EMBL:CAX60988.1, ECO:0000313|Proteomes:UP000008793}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Eb661 {ECO:0000313|EMBL:CAX60988.1,
RC ECO:0000313|Proteomes:UP000008793};
RX PubMed=20565991; DOI=10.1186/1471-2164-11-393;
RA Kube M., Migdoll A.M., Gehring I., Heitmann K., Mayer Y., Kuhl H.,
RA Knaust F., Geider K., Reinhardt R.;
RT "Genome comparison of the epiphytic bacteria Erwinia billingiae and E.
RT tasmaniensis with the pear pathogen E. pyrifoliae.";
RL BMC Genomics 11:393-393(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Metabolite:H+
CC Symporter (MHS) family (TC 2.A.1.6) family.
CC {ECO:0000256|ARBA:ARBA00008240}.
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DR EMBL; FP236843; CAX60988.1; -; Genomic_DNA.
DR RefSeq; WP_013203473.1; NC_014306.1.
DR AlphaFoldDB; D8MVY1; -.
DR STRING; 634500.EbC_34570; -.
DR KEGG; ebi:EbC_34570; -.
DR eggNOG; COG0477; Bacteria.
DR HOGENOM; CLU_001265_39_0_6; -.
DR Proteomes; UP000008793; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17367; MFS_KgtP; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004736; MHS_symport.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR NCBIfam; TIGR00883; 2A0106; 1.
DR PANTHER; PTHR43528; ALPHA-KETOGLUTARATE PERMEASE; 1.
DR PANTHER; PTHR43528:SF1; ALPHA-KETOGLUTARATE PERMEASE; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008793};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 64..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..430
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 434 AA; 47146 MW; 55E909C088BA7B89 CRC64;
MADATSERQP EATADALSTR QRIWAIVGAS SGNLVEWFDF YVYSFCSLYF SHVFFPSGNP
TTQLLQTAGV FAAGFLMRPI GGWLFGYIGD KHGRKKSMLI SVCMMCFGSL VIACLPGYDT
IGVWAPALLL LARLFQGLSV GGEYGTSATY MSEVAVEGKK GFYASFQYVT LIGGQLMALL
TVVVLQQILS DEELRAWGWR IPFAIGAVLA VVALYLRRSL NETSDQKTRQ HKDAGSLRGL
WKHRRAFIMV LGFTAGGSLS FYTFTTYMQK YLVNTSGMDA RTASMLMTAA LFIFMLIQPL
IGALSDKIGR RSSMLIFGGL AAICTVPVLT LLQNISSPWG AFGLVMISLL ITSFYTSISG
ILKAEMFPPE VRALGVGLSY AVANALFGGS AEYVALSLKA AGSETSFFWY VSAMGAVAFL
VSLMLHRRGN GIKL
//
