ID D8PS98_SCHCM Unreviewed; 611 AA.
AC D8PS98;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=SCHCODRAFT_13700 {ECO:0000313|EMBL:EFJ02577.1};
OS Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX NCBI_TaxID=578458 {ECO:0000313|Proteomes:UP000007431};
RN [1] {ECO:0000313|EMBL:EFJ02577.1, ECO:0000313|Proteomes:UP000007431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H4-8 / FGSC 9210 {ECO:0000313|Proteomes:UP000007431};
RX PubMed=20622885; DOI=10.1038/nbt.1643;
RA Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E., Stajich J.E.,
RA de Vries R.P., Record E., Levasseur A., Baker S.E., Bartholomew K.A.,
RA Coutinho P.M., Erdmann S., Fowler T.J., Gathman A.C., Lombard V.,
RA Henrissat B., Knabe N., Kuees U., Lilly W.W., Lindquist E., Lucas S.,
RA Magnuson J.K., Piumi F., Raudaskoski M., Salamov A., Schmutz J.,
RA Schwarze F.W.M.R., vanKuyk P.A., Horton J.S., Grigoriev I.V.,
RA Woesten H.A.B.;
RT "Genome sequence of the model mushroom Schizophyllum commune.";
RL Nat. Biotechnol. 28:957-963(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GL377302; EFJ02577.1; -; Genomic_DNA.
DR RefSeq; XP_003037479.1; XM_003037433.1.
DR AlphaFoldDB; D8PS98; -.
DR GeneID; 9585111; -.
DR KEGG; scm:SCHCO_02489893; -.
DR VEuPathDB; FungiDB:SCHCODRAFT_02489893; -.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_012970_1_0_1; -.
DR InParanoid; D8PS98; -.
DR OMA; WTHTLPG; -.
DR OrthoDB; 2165012at2759; -.
DR Proteomes; UP000007431; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23501; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23501:SF55; SIDEROPHORE IRON TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G03440)-RELATED; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 2.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007431};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 91..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..523
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 577..595
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..598
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 20..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 611 AA; 66630 MW; 193E269712CBC033 CRC64;
MRSNLLSLVR RAPASVVEPT TQDQVVGVDP SADDVKSEKD LESSNEPAHP PSLPHSDEPQ
AHGLDGLTDA NAQPGVKQAA AITQVWSKTS LIIVYIFMFG LYMVNAFQSS ITSNLSAFVT
SDFQSHSLLP VIAIVSNVMS AATYMVVAKV LNLWDRSVGL AVMTMFATLG LILSATCKDI
GTYCASQVFY GIGFSGMIFC VDVITADTSS LKSRGLAYAF TSSPYIITAY AGSKASEHFA
ETNWRWGFGI FAIVLPFVAM PLLATLQYNK HKAAKSGLVV ERESSGRTLM QSILYYTVEF
DILGIFLIAG GLVLFLLPFS IIEQYGDSWR SPGFIAMVII GFFTLVAFGF VEKYVAPKPF
IPWELLTNRT VLGACLIDFT YQISYYCWDD YYSSFLMIVF DTSVAEAGYI ASIFDVVNGV
WLIGVGLLIR RTGRFRWLLM WSVPLFMLFQ GLMIYFRRPG MSIGYIVMCQ VFMAIGGGAI
IICEQVAVLA ASTQNNNAAM LALLGLFGYV GGAVGSAVSG AIWTNTLPGA LQKYLPEDAL
ADWENIYNDI DVQLSYPVGD PVRTAIQAAY GDAQSRMLIA GTSIMALALG FVFLIKNIKL
SDLEQVKGVL F
//
