ID D8PV49_SCHCM Unreviewed; 578 AA.
AC D8PV49;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Pre-mRNA-processing protein 45 {ECO:0000256|ARBA:ARBA00022160, ECO:0000256|RuleBase:RU367140};
DE Flags: Fragment;
GN ORFNames=SCHCODRAFT_105078 {ECO:0000313|EMBL:EFI99967.1};
OS Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX NCBI_TaxID=578458 {ECO:0000313|Proteomes:UP000007431};
RN [1] {ECO:0000313|EMBL:EFI99967.1, ECO:0000313|Proteomes:UP000007431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H4-8 / FGSC 9210 {ECO:0000313|Proteomes:UP000007431};
RX PubMed=20622885; DOI=10.1038/nbt.1643;
RA Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E., Stajich J.E.,
RA de Vries R.P., Record E., Levasseur A., Baker S.E., Bartholomew K.A.,
RA Coutinho P.M., Erdmann S., Fowler T.J., Gathman A.C., Lombard V.,
RA Henrissat B., Knabe N., Kuees U., Lilly W.W., Lindquist E., Lucas S.,
RA Magnuson J.K., Piumi F., Raudaskoski M., Salamov A., Schmutz J.,
RA Schwarze F.W.M.R., vanKuyk P.A., Horton J.S., Grigoriev I.V.,
RA Woesten H.A.B.;
RT "Genome sequence of the model mushroom Schizophyllum commune.";
RL Nat. Biotechnol. 28:957-963(2010).
CC -!- FUNCTION: Involved in pre-mRNA splicing.
CC {ECO:0000256|RuleBase:RU367140}.
CC -!- SUBUNIT: Associated with the spliceosome.
CC {ECO:0000256|RuleBase:RU367140}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU367140}.
CC -!- SIMILARITY: Belongs to the SNW family. {ECO:0000256|ARBA:ARBA00010197,
CC ECO:0000256|RuleBase:RU367140}.
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DR EMBL; GL377303; EFI99967.1; -; Genomic_DNA.
DR RefSeq; XP_003034870.1; XM_003034824.1.
DR AlphaFoldDB; D8PV49; -.
DR STRING; 578458.D8PV49; -.
DR GeneID; 9595394; -.
DR KEGG; scm:SCHCO_02608068; -.
DR VEuPathDB; FungiDB:SCHCODRAFT_02608068; -.
DR eggNOG; KOG2441; Eukaryota.
DR HOGENOM; CLU_006601_2_0_1; -.
DR InParanoid; D8PV49; -.
DR OMA; YGQRRGW; -.
DR OrthoDB; 5490078at2759; -.
DR Proteomes; UP000007431; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-UniRule.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR InterPro; IPR017862; SKI-int_prot_SKIP.
DR InterPro; IPR004015; SKI-int_prot_SKIP_SNW-dom.
DR PANTHER; PTHR12096; NUCLEAR PROTEIN SKIP-RELATED; 1.
DR PANTHER; PTHR12096:SF0; SNW DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF02731; SKIP_SNW; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|RuleBase:RU367140};
KW mRNA splicing {ECO:0000256|RuleBase:RU367140};
KW Nucleus {ECO:0000256|RuleBase:RU367140};
KW Reference proteome {ECO:0000313|Proteomes:UP000007431};
KW Spliceosome {ECO:0000256|RuleBase:RU367140}.
FT DOMAIN 178..334
FT /note="SKI-interacting protein SKIP SNW"
FT /evidence="ECO:0000259|Pfam:PF02731"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 552..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..398
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 578
FT /evidence="ECO:0000313|EMBL:EFI99967.1"
SQ SEQUENCE 578 AA; 63581 MW; C27EB3D2526F7853 CRC64;
MASLAAALPQ PINSGVESDH EEDFRQASTS TTIITRAPIP PYGQRKGWRP TSQADFGDGG
AYPECHVAQY PLDMGKKKTA AGNTIALQVD SEGNVRYDAI ATQGQREGKT VQSQFKDLVP
MLHRQDLDDE ARAMERPSED EVQATTDKTR AALEKLVNGK IKAAQPKNVA SGQGKTSYIR
YTPGQQNGAA GLKQRIIKMS EVVEDPLEPP RYKHKKIPRG PPSPPPPVLR SPPRKATAAE
QKEWMIPPCI SNWKNNKGFT IPLDKRLAAD GRGLQDVTIN DNFAKFSEAL FVADRHAREE
VRQRAIMQQK LAAKEKAAKE ENLRMMAQRA REERGGAPRA AATAQATAAA KASLGAYGSD
SESESDRESA AEDSGEDEEA ARIRDEMRKE KRREREREMR MNNMGAEQRA KMLARQQNRD
ISEKVALGIA KPTLSKESML DSRLFNQESL PGSFGDEESY SLYDRPLFHG STAAAAIYKA
RANIGGEDAE QFGGGTEEGI GKALEADRFG LGPTRVGFEG ANEQEVREGP VQFEKDTGDV
FGLNQFLDEA KTGKKRGLDT EAGGARKRQQ LERANERE
//
