ID D8Q731_SCHCM Unreviewed; 692 AA.
AC D8Q731;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=P-loop containing nucleoside triphosphate hydrolase protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=SCHCODRAFT_109611 {ECO:0000313|EMBL:EFI96343.1};
OS Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX NCBI_TaxID=578458 {ECO:0000313|Proteomes:UP000007431};
RN [1] {ECO:0000313|EMBL:EFI96343.1, ECO:0000313|Proteomes:UP000007431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H4-8 / FGSC 9210 {ECO:0000313|Proteomes:UP000007431};
RX PubMed=20622885; DOI=10.1038/nbt.1643;
RA Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E., Stajich J.E.,
RA de Vries R.P., Record E., Levasseur A., Baker S.E., Bartholomew K.A.,
RA Coutinho P.M., Erdmann S., Fowler T.J., Gathman A.C., Lombard V.,
RA Henrissat B., Knabe N., Kuees U., Lilly W.W., Lindquist E., Lucas S.,
RA Magnuson J.K., Piumi F., Raudaskoski M., Salamov A., Schmutz J.,
RA Schwarze F.W.M.R., vanKuyk P.A., Horton J.S., Grigoriev I.V.,
RA Woesten H.A.B.;
RT "Genome sequence of the model mushroom Schizophyllum commune.";
RL Nat. Biotechnol. 28:957-963(2010).
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; GL377307; EFI96343.1; -; Genomic_DNA.
DR RefSeq; XP_003031246.1; XM_003031200.1.
DR AlphaFoldDB; D8Q731; -.
DR STRING; 578458.D8Q731; -.
DR GeneID; 9592509; -.
DR KEGG; scm:SCHCO_02581649; -.
DR VEuPathDB; FungiDB:SCHCODRAFT_02581649; -.
DR eggNOG; KOG0351; Eukaryota.
DR HOGENOM; CLU_019892_0_0_1; -.
DR InParanoid; D8Q731; -.
DR OMA; NTIYATH; -.
DR OrthoDB; 1662934at2759; -.
DR Proteomes; UP000007431; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007431}.
FT DOMAIN 74..267
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 291..457
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 512..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..527
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 692
FT /evidence="ECO:0000313|EMBL:EFI96343.1"
SQ SEQUENCE 692 AA; 78118 MW; 26EA48166DE45560 CRC64;
MNFPISLDQW LESQTTDVLS AYATATVDPA FLPQVYLQAI MSTQRLHTAL RLCIMCYHTT
LRTHCPRPIQ LDTALSLLAG KDTFLYAGTG TGKTLASILP AYVMDRNGLI IMIVPMKRIQ
ASHARAIREK FGLKVVVVNE ETPRDKEFWQ RHVHDAARKT PGDVQVIITT PEQLRKTAEG
RYSKLGELIR DSFFRSRIRF MVVDEAHCIH TTGFARYGEK AFRIAYGHLD DIKALLGSHV
PWLALTATAP PFMLKTIAHS VLRPSYVTIQ VSLNRPNLTY ACHQVVGSLD RLDNYLCFLT
QPFDLKLQPR VLIFVENMNR TVEIASFLNS KVPESHRHLK IVRHQHSDMS PQYQAHTHAA
FVAEGGTCRI LVSTSTEGTG VDHPDVDVTC VSGDRSSAAE LAQSGGRTMR REDKTGFVIF
FYESWVEDID ITKYPGDVED LDRPGVLNLT GKTTAKERTS RSYAAFVQST SCRRRFFAEY
LGDETAEALV YTGDHCCDNC HDFALENYLP SAPFVEPPPP PPTTKRPREL PGSARPPVSV
QFLKMALEIS LSEWHEQDDL QLVRAPEYIL RAQDITLLSK TRVGTIVTAS DVSTLLRRDR
EWEAEWGIQV LEMVECADEA IRKEWEEKEN EERVNNPKKR KVLSAETIED SDVDDDTMAA
FLNEEAAKRS ALATRNLQQA SRTVNWVTYV DS
//
