ID D8QD27_SCHCM Unreviewed; 1414 AA.
AC D8QD27;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
GN ORFNames=SCHCODRAFT_78429 {ECO:0000313|EMBL:EFI94629.1};
OS Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX NCBI_TaxID=578458 {ECO:0000313|Proteomes:UP000007431};
RN [1] {ECO:0000313|EMBL:EFI94629.1, ECO:0000313|Proteomes:UP000007431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H4-8 / FGSC 9210 {ECO:0000313|Proteomes:UP000007431};
RX PubMed=20622885; DOI=10.1038/nbt.1643;
RA Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E., Stajich J.E.,
RA de Vries R.P., Record E., Levasseur A., Baker S.E., Bartholomew K.A.,
RA Coutinho P.M., Erdmann S., Fowler T.J., Gathman A.C., Lombard V.,
RA Henrissat B., Knabe N., Kuees U., Lilly W.W., Lindquist E., Lucas S.,
RA Magnuson J.K., Piumi F., Raudaskoski M., Salamov A., Schmutz J.,
RA Schwarze F.W.M.R., vanKuyk P.A., Horton J.S., Grigoriev I.V.,
RA Woesten H.A.B.;
RT "Genome sequence of the model mushroom Schizophyllum commune.";
RL Nat. Biotechnol. 28:957-963(2010).
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DR EMBL; GL377309; EFI94629.1; -; Genomic_DNA.
DR RefSeq; XP_003029532.1; XM_003029486.1.
DR STRING; 578458.D8QD27; -.
DR GeneID; 9591358; -.
DR KEGG; scm:SCHCO_02586776; -.
DR VEuPathDB; FungiDB:SCHCODRAFT_02586776; -.
DR eggNOG; ENOG502QQZD; Eukaryota.
DR HOGENOM; CLU_005863_1_0_1; -.
DR InParanoid; D8QD27; -.
DR OMA; NMYTPGC; -.
DR OrthoDB; 2787019at2759; -.
DR Proteomes; UP000007431; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd11856; SH3_p47phox_like; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR024982; Rax2-like_C.
DR InterPro; IPR048266; Rax2-like_second.
DR InterPro; IPR048265; Rax2-like_third.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR31778; BUD SITE SELECTION PROTEIN RAX2; 1.
DR PANTHER; PTHR31778:SF2; BUD SITE SELECTION PROTEIN RAX2; 1.
DR Pfam; PF12768; Rax2; 1.
DR Pfam; PF20842; Rax2_2; 1.
DR Pfam; PF20843; Rax2_3; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007431};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1414
FT /note="SH3 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003120836"
FT TRANSMEM 1233..1264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1357..1414
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 818..849
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1304..1342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 824..849
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1318..1332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1414 AA; 145391 MW; 54A5049909856763 CRC64;
MSTTSPRLLA LLLALHVSPS LAGVPLVDFE RMGTVGLAGA FAGLSVFDDA PTYDEDAATL
LSRSSDDGSL NRLGSTNEGG RISAGCALGD TFYFGGEFSS IEDVSASNVA SYSGNSFSSL
GDGGPDGAVD AVYCDKDNNR VWFGGSFTNP GRGVAIWDAG SNSWSQAPFN GLTGADAHVY
SITTNSSKSS LFFAGSFIAS FRGNGSSTPG TNNPNVPYSA GATPYSSSLV PVPLNNAEVG
GSPSTTNSDY SDINAILCPA GDDGAGNTWL AADGNSALVT IRKYSSLSAS GVRLGNTFLQ
GRGTTGFSVT TIPDNTVQTL QYLDPADNTN KTCSDTCPLS TDSSVLYQDF LFASGPQSIT
GVQITLSEWQ GASAGLHILQ ILSSGAFASA AEDDNGQSCY APGSSNSTST GNWYAKVANT
DISGTTQTVM VSDVDVGTSS SSGPSFTWDL YVSASGEYNM NLLVPGCTNF QNCDARTSVK
VVVFPGLGMD PSVTTVSQTN TDDKQELIYS GPIVPSTDDF HTTVTLSLAD SPEGNGANGQ
YELVADRVQL VLTSANITDD GSGSGNGTGS RGTKRSFGFL EWPLDDSTTG DATSTLDNST
ETAADNLGFG IYSGVGGGSA LTGSSDDAVV AVAHHADGIF VGGNFTLSSG NASGSANIVG
FKNGALVGLS NNGVDGPVRA LQLNGDQLYV GGSFKKNNNG GSTLNGIALY NVQDDSWTAL
GGGVDGTVTG LGIANDELVL VGDFTKLYPT SGSESAINAP GLATWDLQNG GWTNSGGLVV
GSMTLVANGT DDSSHICAGN IAALQKYGAT GMVMLKNGDE NGPSVTPLGV QLSDDGSSSS
STSSSSTTKR YISQIKAHKK ASSWLSKNPL HHLLRRQSSS LDPLPTPPTA AAPAVLAGVF
WTNSSSSKEV AIIGGNFSFS DGSSSSQAIA IYDPESTTIS ALQGGQIDGT VRALLVDGDT
LYIGGDFTLS DTDINGFAIY DLAAQSFHTK GQSPQSNSGS SGSVRSITKS SSKDNTIIVA
GSFAKMGSLT CAGICMLDTE SKQWNALGNG IQGEVASVAY GGDNQAVLIA GGSIAVDNNA
VNVAQFVFEN NTWTALGDGS LPGVVTAVEV NNGNSSSVFA AGVGSGSSTF LYFWNGASWS
SVGSNLQDSE SVAQLTMVPL QDTHDANGAI EPDRMLMVSG SLALADYGNT SSALFDGQAF
VPYLVSSSST GSQGIVAGLF RSLSTFDFTQ HKFLAVGVVI LISIAIAAGV VFLLALIGIL
WTLFSRRDDK VPASEIDEDD DGDSIHHRPS SLLEHINAAT RNTIMGGATT PHSQYDEKGP
STHGHDGETD EQDPFAAGGY VRADTPSDAI HGMLAEEQSR PAHARYSFDG AGEGELQLSA
GAEVEVLDDR DPAWWYARDP RSGQEGVVPA AYLY
//
