ID D8R8B6_SELML Unreviewed; 1457 AA.
AC D8R8B6;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=MHD1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SELMODRAFT_439923 {ECO:0000313|EMBL:EFJ31670.1};
OS Selaginella moellendorffii (Spikemoss).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Lycopodiopsida; Selaginellales; Selaginellaceae; Selaginella.
OX NCBI_TaxID=88036 {ECO:0000313|Proteomes:UP000001514};
RN [1] {ECO:0000313|EMBL:EFJ31670.1, ECO:0000313|Proteomes:UP000001514}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551031; DOI=10.1126/science.1203810;
RA Banks J.A., Nishiyama T., Hasebe M., Bowman J.L., Gribskov M.,
RA dePamphilis C., Albert V.A., Aono N., Aoyama T., Ambrose B.A., Ashton N.W.,
RA Axtell M.J., Barker E., Barker M.S., Bennetzen J.L., Bonawitz N.D.,
RA Chapple C., Cheng C., Correa L.G., Dacre M., DeBarry J., Dreyer I.,
RA Elias M., Engstrom E.M., Estelle M., Feng L., Finet C., Floyd S.K.,
RA Frommer W.B., Fujita T., Gramzow L., Gutensohn M., Harholt J., Hattori M.,
RA Heyl A., Hirai T., Hiwatashi Y., Ishikawa M., Iwata M., Karol K.G.,
RA Koehler B., Kolukisaoglu U., Kubo M., Kurata T., Lalonde S., Li K., Li Y.,
RA Litt A., Lyons E., Manning G., Maruyama T., Michael T.P., Mikami K.,
RA Miyazaki S., Morinaga S., Murata T., Mueller-Roeber B., Nelson D.R.,
RA Obara M., Oguri Y., Olmstead R.G., Onodera N., Petersen B.L., Pils B.,
RA Prigge M., Rensing S.A., Riano-Pachon D.M., Roberts A.W., Sato Y.,
RA Scheller H.V., Schulz B., Schulz C., Shakirov E.V., Shibagaki N.,
RA Shinohara N., Shippen D.E., Soerensen I., Sotooka R., Sugimoto N.,
RA Sugita M., Sumikawa N., Tanurdzic M., Theissen G., Ulvskov P., Wakazuki S.,
RA Weng J.K., Willats W.W., Wipf D., Wolf P.G., Yang L., Zimmer A.D., Zhu Q.,
RA Mitros T., Hellsten U., Loque D., Otillar R., Salamov A., Schmutz J.,
RA Shapiro H., Lindquist E., Lucas S., Rokhsar D., Grigoriev I.V.;
RT "The Selaginella genome identifies genetic changes associated with the
RT evolution of vascular plants.";
RL Science 332:960-963(2011).
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DR EMBL; GL377573; EFJ31670.1; -; Genomic_DNA.
DR RefSeq; XP_002967071.1; XM_002967025.1.
DR EnsemblPlants; EFJ31670; EFJ31670; SELMODRAFT_439923.
DR Gramene; EFJ31670; EFJ31670; SELMODRAFT_439923.
DR KEGG; smo:SELMODRAFT_439923; -.
DR eggNOG; ENOG502R83S; Eukaryota.
DR HOGENOM; CLU_250986_0_0_1; -.
DR InParanoid; D8R8B6; -.
DR OMA; HYYRIRE; -.
DR Proteomes; UP000001514; Unassembled WGS sequence.
DR Gene3D; 1.10.357.50; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR014770; Munc13_1.
DR InterPro; IPR014772; Munc13_dom-2.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR008528; unc-13_homologue.
DR PANTHER; PTHR31280:SF24; C2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR31280; PROTEIN UNC-13 HOMOLOG; 1.
DR Pfam; PF02893; GRAM; 1.
DR PROSITE; PS51258; MHD1; 1.
DR PROSITE; PS51259; MHD2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001514}.
FT DOMAIN 698..819
FT /note="MHD1"
FT /evidence="ECO:0000259|PROSITE:PS51258"
FT DOMAIN 956..1067
FT /note="MHD2"
FT /evidence="ECO:0000259|PROSITE:PS51259"
FT REGION 86..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1319..1339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1390..1415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1436..1457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1325..1339
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1457 AA; 163345 MW; D5347EFBC32907E4 CRC64;
MRILVPFGER EIKFLRRSGT PKSEGLLSTI PSKIALCPRE FAARGRRDRM SAVLSRRTTP
VRGLSLKDCD PERLVAPSSC ILDGSFESPS SSSDEDCEIS VPGDDSSSAL RLPYTPPRKK
WEVSVKNGIV TTKEVSVDEE ISQFSGDEEE EVNDFSEDAY LCEAVLRSVF AVSSPARSLD
DRLADAETVT GAFSTIDRAM LHSVKLRAQK AAQYRRAGLE RQIHGFQRLI RFWLLELSLW
LDALQNNQLQ SVNLDQFEDP QIYERWKQQQ MQEVSTLIAK LGERPSFSGF VQVDVVSVDN
LKPLEVGCVS PLSCSREALK QLHVYSSVTV LPMRSGSEKF GTGDLGKEPT PAFLTDVVPS
TGNAEWQAAS PWIRVSSVQD KVLIEVWDRQ IGGSSFRASG KSKLKKVAPW NQDPFLGQVI
VSFSNIESQA LSQGVMQGKT PLMSYMLADE KGRQKTSGIQ LRFSCSCERF YRDAPSNKLL
LRPPVPDVEK AFDALVSMAY KPQKKGNVDV AAQWHGIVAG FGFHYRIRKQ RCSLGIVMVL
ARNFHINVHI LSSIVEEWLP VCDSARGGQL TKDELGLHTA VVSMLVKPAI DAIENFQTVF
AQNQPSGALS CLLKLLGLVL RWDPDPKEIL IPLKSWIKHL SNVIKLVHGD VTELRTSFKD
TFPEAVSLTA VAVPVYYKLV SAYVINCIRV AQVKMFTKDC ESLIMEMLSF HKDIELAGEK
CELLDLHGIF GDHINQLIST ARTRMVDWVS SSITAEKWEP LSAQSGALFS FSVVDLYFML
GEVMDEMMTR LATLPFGNFY FKNVEDAICT AVRTYVELLE KLCLRDLPEE TTAEGISSSE
LSISKALCVK LNNMNAVMEQ HQDLERRLME TQRNSNGREP LETDADANNL SLFKILERHG
SVKDGLNPKF EEIQRFTEQT IDNVVGSVVE LLQVRIGRDL HLIFDEAAIS DGETLDQNLQ
PLTGHLDQHL MVMNDSSHPV VFQKLITEIC KALVFCLEEF ALNRDEDPNP MTPKQRRLLE
ESLSFFYDYF YGDGQGLDGG QMDTITARLR QILACWDLDT RELCSLYWRA WDQFNTQEEN
RQPEVDGNSG TLHILDYLWL LKQRTDDEAH EIVEQQNFIA NKRMMQFMFG LPKEEELVAS
YSCRNPQKVR GTLYVTPKHI CFADTKMTLA DSRNLYVVPI DRMMRIELSG KRSIVLIPFH
QRPLEFSKLS DRDAVCKTIF DQVVGTGSHL EKCMSPIWSE KGRHAPLKSS NSAVKVFKCW
RQGMLHKYSG TLLVTTAYIL FTQDDKQKVI QMDHTSISKI HASRRGLRPS GVVIELKSGE
DATSGEHADW TTSLESDSGE VSGVQVEAAG AEAAAAVERN HVERMRRADK AEEERGVAAA
RAKAGETIAG IASGSVPSPR RASSPAAPVW RDKDECEAAA KDRARLEKIA KEMADIAATR
KQERETTANP RDLHDLS
//
