ID D8S2I9_SELML Unreviewed; 727 AA.
AC D8S2I9;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=DNA/RNA-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SELMODRAFT_417225 {ECO:0000313|EMBL:EFJ21298.1};
OS Selaginella moellendorffii (Spikemoss).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Lycopodiopsida; Selaginellales; Selaginellaceae; Selaginella.
OX NCBI_TaxID=88036 {ECO:0000313|Proteomes:UP000001514};
RN [1] {ECO:0000313|EMBL:EFJ21298.1, ECO:0000313|Proteomes:UP000001514}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551031; DOI=10.1126/science.1203810;
RA Banks J.A., Nishiyama T., Hasebe M., Bowman J.L., Gribskov M.,
RA dePamphilis C., Albert V.A., Aono N., Aoyama T., Ambrose B.A., Ashton N.W.,
RA Axtell M.J., Barker E., Barker M.S., Bennetzen J.L., Bonawitz N.D.,
RA Chapple C., Cheng C., Correa L.G., Dacre M., DeBarry J., Dreyer I.,
RA Elias M., Engstrom E.M., Estelle M., Feng L., Finet C., Floyd S.K.,
RA Frommer W.B., Fujita T., Gramzow L., Gutensohn M., Harholt J., Hattori M.,
RA Heyl A., Hirai T., Hiwatashi Y., Ishikawa M., Iwata M., Karol K.G.,
RA Koehler B., Kolukisaoglu U., Kubo M., Kurata T., Lalonde S., Li K., Li Y.,
RA Litt A., Lyons E., Manning G., Maruyama T., Michael T.P., Mikami K.,
RA Miyazaki S., Morinaga S., Murata T., Mueller-Roeber B., Nelson D.R.,
RA Obara M., Oguri Y., Olmstead R.G., Onodera N., Petersen B.L., Pils B.,
RA Prigge M., Rensing S.A., Riano-Pachon D.M., Roberts A.W., Sato Y.,
RA Scheller H.V., Schulz B., Schulz C., Shakirov E.V., Shibagaki N.,
RA Shinohara N., Shippen D.E., Soerensen I., Sotooka R., Sugimoto N.,
RA Sugita M., Sumikawa N., Tanurdzic M., Theissen G., Ulvskov P., Wakazuki S.,
RA Weng J.K., Willats W.W., Wipf D., Wolf P.G., Yang L., Zimmer A.D., Zhu Q.,
RA Mitros T., Hellsten U., Loque D., Otillar R., Salamov A., Schmutz J.,
RA Shapiro H., Lindquist E., Lucas S., Rokhsar D., Grigoriev I.V.;
RT "The Selaginella genome identifies genetic changes associated with the
RT evolution of vascular plants.";
RL Science 332:960-963(2011).
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DR EMBL; GL377599; EFJ21298.1; -; Genomic_DNA.
DR RefSeq; XP_002977294.1; XM_002977248.1.
DR AlphaFoldDB; D8S2I9; -.
DR STRING; 88036.D8S2I9; -.
DR EnsemblPlants; EFJ21298; EFJ21298; SELMODRAFT_417225.
DR Gramene; EFJ21298; EFJ21298; SELMODRAFT_417225.
DR KEGG; smo:SELMODRAFT_417225; -.
DR eggNOG; KOG2162; Eukaryota.
DR HOGENOM; CLU_410725_0_0_1; -.
DR InParanoid; D8S2I9; -.
DR Proteomes; UP000001514; Unassembled WGS sequence.
DR GO; GO:0005697; C:telomerase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0070034; F:telomerase RNA binding; IBA:GO_Central.
DR GO; GO:0042162; F:telomeric DNA binding; IBA:GO_Central.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IBA:GO_Central.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR018834; DNA/RNA-bd_Est1-type.
DR InterPro; IPR019458; Est1-like_N.
DR InterPro; IPR045153; Est1/Ebs1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR15696:SF0; PINC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15696; SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7; 1.
DR Pfam; PF10374; EST1; 1.
DR Pfam; PF10373; EST1_DNA_bind; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001514}.
FT DOMAIN 116..224
FT /note="Telomerase activating protein Est1-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10374"
FT DOMAIN 236..342
FT /note="DNA/RNA-binding"
FT /evidence="ECO:0000259|Pfam:PF10373"
FT REGION 46..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 667..713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..681
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 727 AA; 79919 MW; 8A132B24569AE3F7 CRC64;
MKQRSLAKMP GVSLIKVNHK FVVGDPKNKE IYEELWKIHN GGAGLLSRPR DCARKKPPRR
SSEAGIPSTA ASTPPSQAGD LKAKLESKDA DLKEVHALRD DGYGPLLAAP SLSPEIEKAL
WKAHHAKITE FRSQMQRAAE KQKSDRVGKK TLKNVVAPLI DFIASSSNFY SELVSRVRVR
HGLGGTVSDS CDKSLDESEA REFRETCHRL LLRLGDLARY KEVYGVSLGK RNYSTAEDYY
VQASRLCHCE GGAHGQLAIL ATHAGDRVRA VYHYLRSLFV KMPSPTSHSN LLLLLESKSD
AIAEASQGSS NFDNLLRLFE ILLLKTGFDN LQKVLDGTLN ELERSVGTPS KVCDPAEPTM
GKVFLGIQIV TILACSIEDF HLGLVCKTSP PRSSLHETLA CAFKVVRTLA AIGDPTMLPA
LVIFTAGLAG SEDTVRATAE SDELRRSFLD ALERAESFFQ ALSVFSEESL SRLSMSQEEL
TQGRRDALWE DHELQGFVPL GRYHESLNFG FHYLACDSKQ LDWKRLRRLE ASLRALAEMA
GLSKDTTSSQ AETVSTSLGS VLDRQLAELK VDTGLSKNTS SSQADEEAAT ISTNLSSAQL
DDLKVDIADL SKVGFLNEAE EAGSTELEEL PVKFSPSLED SFFAKQFLKS VTGSTDLVLL
EQAPEFPESL EDDHGQGLRD FEDDVIPFPA GDEGATDNSN DEDLQDDIYL PSQSQEDALN
WRSLSSF
//
