ID D8S978_SELML Unreviewed; 580 AA.
AC D8S978;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Adenine/guanine permease AZG1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=SELMODRAFT_419524 {ECO:0000313|EMBL:EFJ18767.1};
OS Selaginella moellendorffii (Spikemoss).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Lycopodiopsida; Selaginellales; Selaginellaceae; Selaginella.
OX NCBI_TaxID=88036 {ECO:0000313|Proteomes:UP000001514};
RN [1] {ECO:0000313|EMBL:EFJ18767.1, ECO:0000313|Proteomes:UP000001514}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551031; DOI=10.1126/science.1203810;
RA Banks J.A., Nishiyama T., Hasebe M., Bowman J.L., Gribskov M.,
RA dePamphilis C., Albert V.A., Aono N., Aoyama T., Ambrose B.A., Ashton N.W.,
RA Axtell M.J., Barker E., Barker M.S., Bennetzen J.L., Bonawitz N.D.,
RA Chapple C., Cheng C., Correa L.G., Dacre M., DeBarry J., Dreyer I.,
RA Elias M., Engstrom E.M., Estelle M., Feng L., Finet C., Floyd S.K.,
RA Frommer W.B., Fujita T., Gramzow L., Gutensohn M., Harholt J., Hattori M.,
RA Heyl A., Hirai T., Hiwatashi Y., Ishikawa M., Iwata M., Karol K.G.,
RA Koehler B., Kolukisaoglu U., Kubo M., Kurata T., Lalonde S., Li K., Li Y.,
RA Litt A., Lyons E., Manning G., Maruyama T., Michael T.P., Mikami K.,
RA Miyazaki S., Morinaga S., Murata T., Mueller-Roeber B., Nelson D.R.,
RA Obara M., Oguri Y., Olmstead R.G., Onodera N., Petersen B.L., Pils B.,
RA Prigge M., Rensing S.A., Riano-Pachon D.M., Roberts A.W., Sato Y.,
RA Scheller H.V., Schulz B., Schulz C., Shakirov E.V., Shibagaki N.,
RA Shinohara N., Shippen D.E., Soerensen I., Sotooka R., Sugimoto N.,
RA Sugita M., Sumikawa N., Tanurdzic M., Theissen G., Ulvskov P., Wakazuki S.,
RA Weng J.K., Willats W.W., Wipf D., Wolf P.G., Yang L., Zimmer A.D., Zhu Q.,
RA Mitros T., Hellsten U., Loque D., Otillar R., Salamov A., Schmutz J.,
RA Shapiro H., Lindquist E., Lucas S., Rokhsar D., Grigoriev I.V.;
RT "The Selaginella genome identifies genetic changes associated with the
RT evolution of vascular plants.";
RL Science 332:960-963(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
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DR EMBL; GL377608; EFJ18767.1; -; Genomic_DNA.
DR RefSeq; XP_002979897.1; XM_002979851.1.
DR AlphaFoldDB; D8S978; -.
DR STRING; 88036.D8S978; -.
DR EnsemblPlants; EFJ18767; EFJ18767; SELMODRAFT_419524.
DR Gramene; EFJ18767; EFJ18767; SELMODRAFT_419524.
DR KEGG; smo:SELMODRAFT_419524; -.
DR eggNOG; ENOG502QQ5E; Eukaryota.
DR HOGENOM; CLU_024508_3_2_1; -.
DR InParanoid; D8S978; -.
DR OMA; AYCTDAF; -.
DR Proteomes; UP000001514; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005345; F:purine nucleobase transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015853; P:adenine transport; IBA:GO_Central.
DR GO; GO:0015854; P:guanine transport; IBA:GO_Central.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001514};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 132..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 513..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 552..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 61260 MW; 268B0F7B4DF1ACA6 CRC64;
MSSSSRSLRE QWNSSIDRLN AAVARSRVGR YFKLEERKSC FTREVRAGTA TFLTMAYILA
VNASILADSG GPCGISDCSL VCSDSTTPIQ RCSGLTPGGI PLTLVKPGAE CKDPGAQNKG
YSDCLDRTKR DLIVATAASS LIGSVIMGVF ANLPLGLAPG MGANAYFAYT VVGFHGSGSI
TYGGALAAVF VEGLIFLGLA ALGLRTRLAK AIPRPVRISS SAGIGLFLAF IGLQSSEGIG
LIGFSPSTLV TLGACPAADR VAVAPVVTNA TTGVSRLMPG ATISSNILCT RNRMEDPTLW
LGVVGFVIIA YALVRGVKGA MIYGIVFVTG ISWFRGTQVT YFPYTDAGNA AYSYFREVVD
VHTIKGTAGA LSFAEIGQSQ FWVALITFLY VDILDTTGTL YSMAKFAGYV DEKGDFEGQY
QAFMSDAAAI VVGSALGTSP VTAFIESSTG IREGGRTGIT ALTVAMYFFL ALFFTPLLAS
IPPWAVGPAL VLVGVLMIKS VKEIEWEDMR EGIPAFITII LMPLTYSIAY GLIGGIGTFV
VLNGLDWLFS KTKRPPSSSD TDEAMKQVDT VETGRALEQV
//
