ID D8SU81_SELML Unreviewed; 863 AA.
AC D8SU81;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=EGF-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SELMODRAFT_425768 {ECO:0000313|EMBL:EFJ11962.1};
OS Selaginella moellendorffii (Spikemoss).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Lycopodiopsida; Selaginellales; Selaginellaceae; Selaginella.
OX NCBI_TaxID=88036 {ECO:0000313|Proteomes:UP000001514};
RN [1] {ECO:0000313|EMBL:EFJ11962.1, ECO:0000313|Proteomes:UP000001514}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551031; DOI=10.1126/science.1203810;
RA Banks J.A., Nishiyama T., Hasebe M., Bowman J.L., Gribskov M.,
RA dePamphilis C., Albert V.A., Aono N., Aoyama T., Ambrose B.A., Ashton N.W.,
RA Axtell M.J., Barker E., Barker M.S., Bennetzen J.L., Bonawitz N.D.,
RA Chapple C., Cheng C., Correa L.G., Dacre M., DeBarry J., Dreyer I.,
RA Elias M., Engstrom E.M., Estelle M., Feng L., Finet C., Floyd S.K.,
RA Frommer W.B., Fujita T., Gramzow L., Gutensohn M., Harholt J., Hattori M.,
RA Heyl A., Hirai T., Hiwatashi Y., Ishikawa M., Iwata M., Karol K.G.,
RA Koehler B., Kolukisaoglu U., Kubo M., Kurata T., Lalonde S., Li K., Li Y.,
RA Litt A., Lyons E., Manning G., Maruyama T., Michael T.P., Mikami K.,
RA Miyazaki S., Morinaga S., Murata T., Mueller-Roeber B., Nelson D.R.,
RA Obara M., Oguri Y., Olmstead R.G., Onodera N., Petersen B.L., Pils B.,
RA Prigge M., Rensing S.A., Riano-Pachon D.M., Roberts A.W., Sato Y.,
RA Scheller H.V., Schulz B., Schulz C., Shakirov E.V., Shibagaki N.,
RA Shinohara N., Shippen D.E., Soerensen I., Sotooka R., Sugimoto N.,
RA Sugita M., Sumikawa N., Tanurdzic M., Theissen G., Ulvskov P., Wakazuki S.,
RA Weng J.K., Willats W.W., Wipf D., Wolf P.G., Yang L., Zimmer A.D., Zhu Q.,
RA Mitros T., Hellsten U., Loque D., Otillar R., Salamov A., Schmutz J.,
RA Shapiro H., Lindquist E., Lucas S., Rokhsar D., Grigoriev I.V.;
RT "The Selaginella genome identifies genetic changes associated with the
RT evolution of vascular plants.";
RL Science 332:960-963(2011).
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DR EMBL; GL377642; EFJ11962.1; -; Genomic_DNA.
DR RefSeq; XP_002986880.1; XM_002986834.1.
DR AlphaFoldDB; D8SU81; -.
DR STRING; 88036.D8SU81; -.
DR EnsemblPlants; EFJ11962; EFJ11962; SELMODRAFT_425768.
DR Gramene; EFJ11962; EFJ11962; SELMODRAFT_425768.
DR KEGG; smo:SELMODRAFT_425768; -.
DR eggNOG; KOG3538; Eukaryota.
DR HOGENOM; CLU_331881_0_0_1; -.
DR InParanoid; D8SU81; -.
DR Proteomes; UP000001514; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 3.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013111; EGF_extracell.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR PANTHER; PTHR13723:SF316; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07974; EGF_2; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 3.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00209; TSP1; 3.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 3.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50092; TSP1; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001514};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..863
FT /note="EGF-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003123035"
FT TRANSMEM 669..691
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 608..634
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS01248"
FT DOMAIN 608..619
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS00022"
FT REGION 743..801
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 834..863
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 743..769
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 863 AA; 92810 MW; 52528E15C55CB011 CRC64;
MAMKIALLYI LASRFFIDPF IALGLLSRNQ RDALCTIGST CESLPPLDLA VDYDSDHFWV
PLSWNPCSNE CGGGTQTAAL GCYASNLTRV SSSICEDLPK LSVEQPCNAI ECPSYTVYRS
PWSECSKTCG TGYQTREVLC HDNLGSLVHS QHCDLEESYV ESQLCNTDAC EASYWTLPAW
SACDAPCGGG RQKRIPTCHS TRTEVSICTG ERPKTEQMCN TQACSTHAWL VGPWKSCPYE
CEATTDRLVQ CVDGYGFEQP DSECPGSKPA STISCDQPHI SCSDCLYDCF GHGVCKPDQC
SCYDGWTGKY CQTPSNCHGS LGYSEQAKAR CCHLVDVNQR CCSTTASLDK DGNCCASGVL
DSLGVCDGVA TMIDFEGKPC STIRDEKGLC CISGVLDECH ICDGDGTTCS TDMTLYLNVT
GFAQAIQEGA FQKFLTSTMS RLASKLRIAD EALTVAEVRM ISPGGETCAV DALQDSLCSQ
DEQINGLAVV NATVFPTSPD MVIKKRKDVL AALQPGPLSS SLTVLPEALS ADLLFVGDVR
RAGVCGNGLC ERGERCTSVG ASATTFRTSC CLQDCPYVSA VCPAPMAGPM KNKTCSGRGI
CLEASGQCDC FRGYAGSDCS ICAWGWIQTP SGACVMLPDP HSLSKLVAAY KEQKPKPAPT
HRHRKGIDAS GTVILLALCG VCLALLLLLI VAEHHQQRRV GVHPEPANDP PANGGERAAT
KWRSSYLGPH SEYDVIPITP RPPTQTTQTI ETPPSQVLPG ESSRRWSSRR SFFGGKDGTG
KRSFRDGSPS ELELQSGPNL VTTGEDLTEE EQAKMSERVR KELRGSRSAK FVTGYLTDSE
DSDGGDEHNT HCCTPDSPAI VRT
//
