ID D8SYZ7_SELML Unreviewed; 1797 AA.
AC D8SYZ7;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
GN ORFNames=SELMODRAFT_128226 {ECO:0000313|EMBL:EFJ10314.1};
OS Selaginella moellendorffii (Spikemoss).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Lycopodiopsida; Selaginellales; Selaginellaceae; Selaginella.
OX NCBI_TaxID=88036 {ECO:0000313|Proteomes:UP000001514};
RN [1] {ECO:0000313|EMBL:EFJ10314.1, ECO:0000313|Proteomes:UP000001514}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551031; DOI=10.1126/science.1203810;
RA Banks J.A., Nishiyama T., Hasebe M., Bowman J.L., Gribskov M.,
RA dePamphilis C., Albert V.A., Aono N., Aoyama T., Ambrose B.A., Ashton N.W.,
RA Axtell M.J., Barker E., Barker M.S., Bennetzen J.L., Bonawitz N.D.,
RA Chapple C., Cheng C., Correa L.G., Dacre M., DeBarry J., Dreyer I.,
RA Elias M., Engstrom E.M., Estelle M., Feng L., Finet C., Floyd S.K.,
RA Frommer W.B., Fujita T., Gramzow L., Gutensohn M., Harholt J., Hattori M.,
RA Heyl A., Hirai T., Hiwatashi Y., Ishikawa M., Iwata M., Karol K.G.,
RA Koehler B., Kolukisaoglu U., Kubo M., Kurata T., Lalonde S., Li K., Li Y.,
RA Litt A., Lyons E., Manning G., Maruyama T., Michael T.P., Mikami K.,
RA Miyazaki S., Morinaga S., Murata T., Mueller-Roeber B., Nelson D.R.,
RA Obara M., Oguri Y., Olmstead R.G., Onodera N., Petersen B.L., Pils B.,
RA Prigge M., Rensing S.A., Riano-Pachon D.M., Roberts A.W., Sato Y.,
RA Scheller H.V., Schulz B., Schulz C., Shakirov E.V., Shibagaki N.,
RA Shinohara N., Shippen D.E., Soerensen I., Sotooka R., Sugimoto N.,
RA Sugita M., Sumikawa N., Tanurdzic M., Theissen G., Ulvskov P., Wakazuki S.,
RA Weng J.K., Willats W.W., Wipf D., Wolf P.G., Yang L., Zimmer A.D., Zhu Q.,
RA Mitros T., Hellsten U., Loque D., Otillar R., Salamov A., Schmutz J.,
RA Shapiro H., Lindquist E., Lucas S., Rokhsar D., Grigoriev I.V.;
RT "The Selaginella genome identifies genetic changes associated with the
RT evolution of vascular plants.";
RL Science 332:960-963(2011).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|ARBA:ARBA00006460, ECO:0000256|RuleBase:RU004279}.
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DR EMBL; GL377654; EFJ10314.1; -; Genomic_DNA.
DR RefSeq; XP_002988518.1; XM_002988472.1.
DR STRING; 88036.D8SYZ7; -.
DR EnsemblPlants; EFJ10314; EFJ10314; SELMODRAFT_128226.
DR Gramene; EFJ10314; EFJ10314; SELMODRAFT_128226.
DR KEGG; smo:SELMODRAFT_128226; -.
DR eggNOG; KOG0260; Eukaryota.
DR HOGENOM; CLU_000487_3_0_1; -.
DR InParanoid; D8SYZ7; -.
DR OMA; MVQYDRT; -.
DR Proteomes; UP000001514; Unassembled WGS sequence.
DR GO; GO:0005665; C:RNA polymerase II, core complex; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd02584; RNAP_II_Rpb1_C; 1.
DR CDD; cd02733; RNAP_II_RPB1_N; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.150.390; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.30.1360.140; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 3.30.1490.180; RNA polymerase ii; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 2.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR000684; RNA_pol_II_repeat_euk.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR007075; RNA_pol_Rpb1_6.
DR InterPro; IPR007073; RNA_pol_Rpb1_7.
DR InterPro; IPR038593; RNA_pol_Rpb1_7_sf.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR Pfam; PF04990; RNA_pol_Rpb1_7; 1.
DR Pfam; PF05001; RNA_pol_Rpb1_R; 27.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
DR PROSITE; PS00115; RNA_POL_II_REPEAT; 19.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001514};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 253..559
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
FT REGION 161..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1557..1797
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1797 AA; 200676 MW; 61F57E22E861B192 CRC64;
MDLRFPYSPA ELARVKRVQF GLMSPDEIRQ MSVCKIESSE TYDRGKPKSG GLSDPRLGTI
DRQTKCETCG GSMAECPGHF GHLELAKPMF HIGFLKTVLA LLRCVCYNCS HILALEVCRE
TLLLCFIFGL FKLAKKAKNP KQRLKKVLEC CKNKQKCEGN NNDMDGEQDD QEGEQKGHGG
CGAQQPKITI DGMKIIAEFK VPKKKGDDQD QYLPEPVERK QQLTAERVLG ILKRISDEEC
RILGLDPQFA RPDWMILQVL PIPPPPVRPS VMMDSSARSE DDLTHQLAMI IRHNNNLKRQ
EQNGAPTHII NEFTQLLQFH IATYFDNDLP GQPRATQRSG RPIKSICQRL KAKEGRIRGN
LMGKRVDFSA RTVITPDPNI NIDELGVPWS IALNLTYPET VTPYNLERLK ELVEYGPHPP
PGKTGAKYII REDGQRLDLR YLKKSSDRHL ELGYKVERHL CDGDFVLFNR QPSLHKMSIM
GHRIRIMPYS TFRLNLSVTS PYNADFDGDE MNMHVPQSFE TRAEVSELMI VPKCIVSPQS
NRPVIGIVQD TLLGCRKVTK RDTFIEKDVF MNILMWWEDF DGKVPTPAIV KPRPIWTGKQ
IFSLIIPKQI NMVRTAAWHN DSETGDNSPG DTMVRIEKGE LLTGTLCKKT LGTSSGSLIH
VIWEEVGPDA ARKFLGHTQW LVNYWLLQHG FSIGIGDTIA DSATMEKIND TIFKAKNEVK
DLIKIAQEKQ LESQPGRTMM ESFENRVNQV LNRARDEAGS SAQKSLSESN NVKAMVTAGS
KGSFINISQM IACVGQQNVE GKRIPFGFID RTLPHFTKDD YGPESRGFVE NSYLRGLTPQ
EFYFHAMGGR EGLIDTAVKT SETGYIQRRL VKAMEDVMVK YDGTVRNSLG DVIQFLYGED
GMDAVWIESQ HLDSIKMKKK NFDMTYKFEV DNENWNPDYM ASDCAEDIKT IQEIRNVFDA
EVQKLEADRK QLGLEIATSG EPHWPLPVNL KRLIWNAQKI FKIEMKKPSD MHPMEIVEAV
DKLQEKLLVV PGDDPISIEA QKNATLFFNC LLRSTFASKR VLKEYRLTKE AFEWVIGEIE
TRFLQSLVAP GEMIGCVAAQ SIGEPATQMT LNTFHYAGVS AKNVTLGVPR LREIINVAKK
IKTPSLYVHL KPEVSKEKER AKNVQCALEY TTLRSVTQAT EIWYDPDPMS TIIEEDVEFV
KSYYEMPDED VTPDKISPWL LRIELNREMM VDKKLSMADI AEKINLEFVD DLTCIFNDDN
AEKLILRVRI MNDDVSKGGE VDQSDDDVFL KKIESNMLTE MALRGIPDIH KVFIREHKRQ
RFDEHEGFKT ETEWMLDTEG VNMLAVMCNE DVDATRTVSN HLIEVIEVLG IEAVRQALLK
ELREVISFDG SYVNYRHLAI LCDVMTYRGH LMAITRHGIN RNDTGPMMRC SFEETVDILL
DAAVFAEADH LRGVTENIML GQLAPIGTGD FGLLLNDKML EHAIELQLPS YMETADFGLG
GVTGTPHHEG MMSPSYLLSP NLRASPITDA QFSPYVGGIT FSPGAYSPLS PAYSPAGYSP
ASPNYSPSSP TYSPSSPAYS PASPAYSPSS PGYSPASPAY SPTSPSYSPT SPSYSPTSPS
YSPTSPSYSP TSPSYSPTSP SYSPTSPSYS PTSPSYSPTS PSYSPTSPSY SPTSPSYSPT
SPSYSPTSPS YSPTSPSYSP TSPSYSPTSP SYSPTSPSYS PTSPSYSPTS PSYSPTSPAY
SPTSPSYSPT SPSYSPTSPS YSPTSPAYSP TSPAYSPSSH TYSPSSLKYS SASPSYR
//
