ID D8U239_VOLCA Unreviewed; 3085 AA.
AC D8U239;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
GN ORFNames=VOLCADRAFT_105651 {ECO:0000313|EMBL:EFJ46295.1};
OS Volvox carteri f. nagariensis.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Volvocaceae; Volvox.
OX NCBI_TaxID=3068 {ECO:0000313|Proteomes:UP000001058};
RN [1] {ECO:0000313|EMBL:EFJ46295.1, ECO:0000313|Proteomes:UP000001058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=f. Nagariensis / Eve {ECO:0000313|Proteomes:UP000001058};
RX PubMed=20616280; DOI=10.1126/science.1188800;
RA Prochnik S.E., Umen J., Nedelcu A.M., Hallmann A., Miller S.M., Nishii I.,
RA Ferris P., Kuo A., Mitros T., Fritz-Laylin L.K., Hellsten U., Chapman J.,
RA Simakov O., Rensing S.A., Terry A., Pangilinan J., Kapitonov V., Jurka J.,
RA Salamov A., Shapiro H., Schmutz J., Grimwood J., Lindquist E., Lucas S.,
RA Grigoriev I.V., Schmitt R., Kirk D., Rokhsar D.S.;
RT "Genomic analysis of organismal complexity in the multicellular green alga
RT Volvox carteri.";
RL Science 329:223-226(2010).
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DR EMBL; GL378352; EFJ46295.1; -; Genomic_DNA.
DR RefSeq; XP_002952742.1; XM_002952696.1.
DR STRING; 3068.D8U239; -.
DR GeneID; 9627246; -.
DR KEGG; vcn:VOLCADRAFT_105651; -.
DR eggNOG; KOG0505; Eukaryota.
DR eggNOG; KOG2101; Eukaryota.
DR eggNOG; KOG2926; Eukaryota.
DR InParanoid; D8U239; -.
DR OrthoDB; 2265421at2759; -.
DR Proteomes; UP000001058; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:InterPro.
DR CDD; cd06093; PX_domain; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.30.70.250; Malonyl-CoA ACP transacylase, ACP-binding; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 2.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22999; PX SERINE/THREONINE KINASE PXK; 1.
DR PANTHER; PTHR22999:SF23; SORTING NEXIN-16; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00294; PfkB; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000001058}.
FT REPEAT 837..869
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 870..906
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 2156..2273
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 255..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 332..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1420..1446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1477..1502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1517..1587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1771..1862
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1961..2074
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2094..2141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2334..2356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2435..2469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2506..2525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2541..2634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2737..2771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2879..2963
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..288
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1420..1434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1771..1790
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1977..1993
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2013..2027
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2098..2118
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2119..2141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2580..2594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2743..2762
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2913..2938
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2947..2961
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3085 AA; 318746 MW; 0A0834AB27FD7B69 CRC64;
MECVCFTLIV DDIVLPHGET VMEALGGGGP QTLFGYQLVT NQSAAVGLSA GVGPDLPQRC
KAWLESLGVD TSGLVPYQRP TPRAWQVFEE WGRRTQIWRG RDDPCEELYE MLRPKYDTMP
AHFQRSCNYH LGVHPLHPPR RLMSQLRRAA HANGGVLSIE PYTSAESAAT PGQVSELLAH
CDIFSPNEGE AESIVGPGSP EQLALRLLSL SPPGGADLVV VRCGPEGALV ARRRQPQPLV
SAEAAVGPVT ERALANQHGQ QDGGADGAGL RQDGRRKGEQ AEEHVEEHVE VEVEVYRVPA
VADTALVDAT GCGNAFCGGF LAALYRGGGG NGSGSGNGDD ACGNTGDQAD GVGDTSTQGG
SPEAAVATAA AGLEVAGRVD AAGCAPSEGE GQEGLPPPWV RTGDLRLAGA WGCVAASFMA
EERGVPLKRV AELQGMDLSN TLWLCFICAG LTCIRNIISQ RLGADGRGRA SGDALARVPT
VDTEVSQRHT KAASAAYDRS FGRTAATSAT ASTLQEAQTP RPRARVTVSQ PGVPLQRTAA
SAQLLRAVTV AGTSPSNHLP TYMDSAHTTA LARAAAGRRR LQITAANQTD CLEESFSIRG
HLGQEGRTRA SIHTHKHIHN VTPPGVPIVQ ITQRLLGRGC PSPSSAARNQ TLTTERGVIL
KGLIIWDTFQ HKDRDGGTRY LTLGATASDL VVPRSGGPRS RNCNREAETS QPPYLPTVGL
TVLSVICCAW LLRSKRVYAL TVVICHQGQG EGTSKEYTQV IRINFFLSSS FDTITPGFPP
PSLPIMPRDM TGTGRYPPQP RHPALAFYSA VRMGDPELLT RIMQTQVDPY FVTQDNGAGA
PIHFAVTYRQ LDMVHHLLNL GASVNQRDPR GFTPLHRAAH LAHLDGYLEM YEYLLSRGAD
PAILTEDYDS YLDPGAKTPQ QVAVDDPRVR AALQALEDKY ASVPKAPRAH PDLGDWWTLY
DYGPEIVGAW PHNYVHPYPE EAARRRAKAE KRSQREARRE KRAAFLSSLE AGGDGSEVLG
SYGSPAQASS VAAAVPPPPP LPVATNRVVF LFPGQGSQAV GMLSAAANLP AVAAMLNTAR
QVLGYDLLEI CTKGPQSVLD DTKVAQPALF VAGLAAVELL RQSDPRVVDS CSACAGLSLG
EYTALVFAGA LSFEEGLRVV KARGEAMAAA AAAAPPGSGL RPHGMLSVVG LPDSDLSRLA
EEAEAGGAPG SVCRIANYLF PQFCYRTVHL PQHSFLGSSF TRSRAPPYLP SCGLLCIAVQ
QALAQVTFRA PRIPVFSNVI ARPFPTDPRD IPALLGRQLV EPVQWEATLA ALLAASSLPA
ASSLPLALYE LGPGSCKSIF GSIPLAIVLV AAAQWHLRAL GPACAHRARA HHSPPHDLAQ
SAASFAAGLW LLLDYTLDCV FLGDGALLWR KGARVQGPLI IRGSSSSSNG SQPHTAPRHH
DEHQLQARPR YQLREVEAAG EAVGPGFQVE FPCPQQRLTG QQPQAQQGQT QRQPPSSTTS
RNAQILRERL GCVKGARDVT HGSQPSAPWS ADGGGGGGSS SGGGSRVKGS MSLSLPRVPL
PSGGGGGGGA GVGGGGGGTR AASRPDPDAW RVQVGSKVVE FAWEKLCGAI VQTWVYDTWW
ALLSPDREFP AEVRRLLFAA FGRLAYPSIS GICFTHPWDV CEALIASLEL YRSALEHLGG
EQQLEARALR HAAQDLVGVL WPDDDMLCGR LRPLLRELLS SCVLRPVMML ASPHTINRLL
AAALSPLPEE TTTAAAAAAT AAAAAAATTN SPSASAASPH TGSSGGGSGA ETARGSGYTG
GGGTSPTVPA RGAHTAAANS ADGALPFARL RTASPPSSSS SSSPPPWPSP PSYRGLSAQR
QRTAAAALPG AASGTAANAA AAATATVTAA AAASKPLRSP PVAATATASG PAAAAAAAAT
AAAVADAAAR AAAEGSLEFE RRVAANAAAE ATLMRRMAGS TLGARSGSTR AADNLRWCPP
APPPPPAPPR QQLAQPPDQL QHGGDGDGGS GSERTGFCSQ VQLNEEGSET RRALGRGVSS
GVHRRSCSSD AAAAPAAKPT HSGGATGSGT GSGSGGASFS LAWFDFDFGG GLMLPWQRPG
PEPLPLSPPQ PPPPPQQQQQ QSQHQQQELK PSPLLTSAAA GSGGGSGSGC CWFRASVAAF
EMVSEPLGFG LTAEYVVYKI RVADVDSGEE WTVARRFRSF EAMAVKLAAA MPRYAHLVRA
LPPKRLFVHT ADVAFINSRR ADLDAYLQQL LGVRELAECP VLREFLLPNP SPAHTAASNA
LDGSAIGATT APSLAASLAG LLGPPLSHTA AAVASASAGR NLLERVALDL RGLRKGPNSR
RRRSAEQRVA PLAAFGGGGG GGGGIRPFAW LGRRDDNTAT AAAAAAAAAA EAAAPPPPQS
SMPVGIGVPG SGGAEAAAVA AAGLSSWSEE YDDLLDEEEE DDLTTLPPAD VPAVAAAPPP
PAAAVTSQGS GGGVGFRFGL QNWGTGGGGG SGGSSFSFPS VRARFRHKAH QQPQPGCPDG
SSKTSASLSA VTATVTATAT APSLTAESSP CPSGASWHAG AANGGLSSVG GPPPPSATAP
SRDAQAQPLP LTPVTSEAPA TAAASGAASE VPGRAASALH PPSRPGGVAG VTIADAGGAG
SPAALHRSPV PEAATVTTVP LPLPLRPSID TALATHRSPG TSSTFRAVTA ATSGVGGGAR
WHSQAAVSKE CTTRTQAASA TTAAAAASST SAAKVFSAPS SPIAPTHLPP PRPAPARPPS
PPLGGGDGGD VSSATAAAAA IGVGKDVATA SASGVSAPLY ELIDVLFGLQ GQGFFRRQVI
SVTRQGLSLF AGGAIDSWIT TRLRDLTSEH HLARLLLLLH GTLFPGGAWS AVATAAASGR
GAGQPMPTPS SSSPAAEAAE AEAGSSPGPT LLPSSTSPSP SPPPPPPPPP PAAAAVPRWQ
PNPPIHADTY LDSSSQPPDA QQLADRVRAR LFSRPPTMLI NVVGARTYSR ALSDVWGMTQ
SRTFVLQLAY SLLTTLLIRL FPELTQQLQH LQLKGGGVAR AGEERQESGW SRKLALCGRG
QQECKEQELT YAVQLVSNTP SDSKA
//
