ID D8U2M3_VOLCA Unreviewed; 294 AA.
AC D8U2M3;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 22-FEB-2023, entry version 38.
DE RecName: Full=BFN domain-containing protein {ECO:0000259|PROSITE:PS51658};
GN ORFNames=VOLCADRAFT_121109 {ECO:0000313|EMBL:EFJ46161.1};
OS Volvox carteri f. nagariensis.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Volvocaceae; Volvox.
OX NCBI_TaxID=3068 {ECO:0000313|Proteomes:UP000001058};
RN [1] {ECO:0000313|EMBL:EFJ46161.1, ECO:0000313|Proteomes:UP000001058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=f. Nagariensis / Eve {ECO:0000313|Proteomes:UP000001058};
RX PubMed=20616280; DOI=10.1126/science.1188800;
RA Prochnik S.E., Umen J., Nedelcu A.M., Hallmann A., Miller S.M., Nishii I.,
RA Ferris P., Kuo A., Mitros T., Fritz-Laylin L.K., Hellsten U., Chapman J.,
RA Simakov O., Rensing S.A., Terry A., Pangilinan J., Kapitonov V., Jurka J.,
RA Salamov A., Shapiro H., Schmutz J., Grimwood J., Lindquist E., Lucas S.,
RA Grigoriev I.V., Schmitt R., Kirk D., Rokhsar D.S.;
RT "Genomic analysis of organismal complexity in the multicellular green alga
RT Volvox carteri.";
RL Science 329:223-226(2010).
CC -!- FUNCTION: Bifunctional nuclease with both RNase and DNase activities.
CC Involved in basal defense response. Participates in abscisic acid-
CC derived callose deposition following infection by a necrotrophic
CC pathogen. {ECO:0000256|ARBA:ARBA00025428}.
CC -!- SIMILARITY: Belongs to the bifunctional nuclease family.
CC {ECO:0000256|ARBA:ARBA00009095}.
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DR EMBL; GL378353; EFJ46161.1; -; Genomic_DNA.
DR RefSeq; XP_002952911.1; XM_002952865.1.
DR AlphaFoldDB; D8U2M3; -.
DR STRING; 3068.D8U2M3; -.
DR GeneID; 9627572; -.
DR KEGG; vcn:VOLCADRAFT_121109; -.
DR eggNOG; ENOG502S7NU; Eukaryota.
DR InParanoid; D8U2M3; -.
DR OrthoDB; 304718at2759; -.
DR Proteomes; UP000001058; Unassembled WGS sequence.
DR GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR Gene3D; 3.10.690.10; Bifunctional nuclease domain; 1.
DR InterPro; IPR036104; BFN_sf.
DR InterPro; IPR003729; Bi_nuclease_dom.
DR PANTHER; PTHR15160:SF1; VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR; 1.
DR PANTHER; PTHR15160; VON HIPPEL-LINDAU PROTEIN; 1.
DR Pfam; PF02577; BFN_dom; 1.
DR SUPFAM; SSF103256; Hypothetical protein TM0160; 1.
DR PROSITE; PS51658; BFN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001058}.
FT DOMAIN 82..221
FT /note="BFN"
FT /evidence="ECO:0000259|PROSITE:PS51658"
SQ SEQUENCE 294 AA; 32510 MW; 65AF32AECBFAD325 CRC64;
MAQLFCTPLP AGRAFRGIAT PVCSTLGAAI RCRGTGQALS SQAQTCGRSS FAGPGNRCGR
ILVRAYEQGS SGPSRDPSLD GFVEVKVDQV RLGQGNAVVY LRILDGRERV LPVHIGENES
NALLKEINKQ RQMRPLTHDV MKNILKEIKF RVVKIRITDI VANTYYARIH LARVNDATGL
PDPGTEVDVD ARPSDAINLA VRFGSPMYVA KKIADTAGTP YPDQPVTTTS ETNTEIVRSV
RETMASFEDP TVMYTLQKDL AVKEERFEDA HQMQQLIYHE MTHNALLRLR CLGR
//
