ID D8UHF7_VOLCA Unreviewed; 754 AA.
AC D8UHF7;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN Name=splh3 {ECO:0000313|EMBL:EFJ40817.1};
GN ORFNames=VOLCADRAFT_84321 {ECO:0000313|EMBL:EFJ40817.1};
OS Volvox carteri f. nagariensis.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Volvocaceae; Volvox.
OX NCBI_TaxID=3068 {ECO:0000313|Proteomes:UP000001058};
RN [1] {ECO:0000313|EMBL:EFJ40817.1, ECO:0000313|Proteomes:UP000001058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=f. Nagariensis / Eve {ECO:0000313|Proteomes:UP000001058};
RX PubMed=20616280; DOI=10.1126/science.1188800;
RA Prochnik S.E., Umen J., Nedelcu A.M., Hallmann A., Miller S.M., Nishii I.,
RA Ferris P., Kuo A., Mitros T., Fritz-Laylin L.K., Hellsten U., Chapman J.,
RA Simakov O., Rensing S.A., Terry A., Pangilinan J., Kapitonov V., Jurka J.,
RA Salamov A., Shapiro H., Schmutz J., Grimwood J., Lindquist E., Lucas S.,
RA Grigoriev I.V., Schmitt R., Kirk D., Rokhsar D.S.;
RT "Genomic analysis of organismal complexity in the multicellular green alga
RT Volvox carteri.";
RL Science 329:223-226(2010).
CC -!- FUNCTION: Protein transport. Probably involved in vesicular traffic.
CC {ECO:0000256|ARBA:ARBA00025673}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL378406; EFJ40817.1; -; Genomic_DNA.
DR RefSeq; XP_002958086.1; XM_002958040.1.
DR AlphaFoldDB; D8UHF7; -.
DR STRING; 3068.D8UHF7; -.
DR GeneID; 9623183; -.
DR KEGG; vcn:VOLCADRAFT_84321; -.
DR eggNOG; KOG0922; Eukaryota.
DR InParanoid; D8UHF7; -.
DR OrthoDB; 5488182at2759; -.
DR Proteomes; UP000001058; Unassembled WGS sequence.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF234; ATP-DEPENDENT RNA HELICASE DHX40-RELATED; 1.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000001058}.
FT DOMAIN 17..199
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 222..399
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 552..571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 718..733
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 754 AA; 81322 MW; 0C42915599E80759 CRC64;
MSNTGSLPIR IFSKDILAAV KNNDVIVVIG ETGSGKTTQL SQILYEAGYA SDGMIAVTQP
RRVGAVTVAK RVAEERGVQL GREVGYAVRF EDCSSSATRI KYLTDGTLLR ECLEDPQLKR
YSIIVLDEAH ERSLNTDILF GLLKRLVRSR NTQRAKEGET EAGSSSSRAR RLKLVITSAT
LDGEKFSAYF GNCPVFNVPG RCFPVDIIHT LEDHLSDYVS AAIDTVMQIH TSQPDGDILM
FLTGQAEIEK AIGRIHQAVA SLPAGSAGPL VVLPLYASLP PELQVRVFRP APEGTRRCIV
ATNVAETSIT VEGVVYVVDP GVVKQKSYQP ASGMDSLDVV AISRVQATQR AGRAGRTKPG
KCFRLYTRTY YEHKMPNVTA PEIQRSSLVG TVLYLKSLQL EVDVLNFDFL DPPAVGALED
ALRQLLVLDA LDSDGNVTPL GLRMSGLPLE PALARALLAA RELGCVREMI SVAAMLSSEH
VFLAGQGPGD VAAGDHPHGQ DSRRYVGLGD HVLLLRLWEG WEAAGCSREF AREYGLDLRG
LNFARDIRRQ LDGRQQRPSS PQCRWGGGTA PGAARASAAQ VDALRHVLTI GFANKLARRL
PRHNGYKTLH AVSGQLAQLH PSCAQLREDA DGLLPEFLVY HELVATSRPF LRQVCPSRAE
WVADVLPKIM SADVRRLSQG SSRGLGGAAG SGQPRSPGGG DGGGGGDRGG AGGPQEGPEA
RRNDDKAVDA ARARYLARKQ QQPPQPVGKS GHKR
//
