ID D9N139_CAEEL Unreviewed; 458 AA.
AC D9N139;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 88.
DE SubName: Full=EF-hand domain-containing protein {ECO:0000313|EMBL:CBO23318.1};
GN ORFNames=C56A3.6 {ECO:0000313|EMBL:CBO23318.1,
GN ECO:0000313|WormBase:C56A3.6d}, CELE_C56A3.6
GN {ECO:0000313|EMBL:CBO23318.1};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CBO23318.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CBO23318.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CBO23318.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284605; CBO23318.1; -; Genomic_DNA.
DR RefSeq; NP_001256521.1; NM_001269592.1.
DR AlphaFoldDB; D9N139; -.
DR SMR; D9N139; -.
DR EPD; D9N139; -.
DR EnsemblMetazoa; C56A3.6d.1; C56A3.6d.1; WBGene00008345.
DR GeneID; 179837; -.
DR AGR; WB:WBGene00008345; -.
DR WormBase; C56A3.6d; CE32339; WBGene00008345; -.
DR OrthoDB; 1020411at2759; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00008345; Expressed in germ line (C elegans) and 4 other cell types or tissues.
DR ExpressionAtlas; D9N139; baseline and differential.
DR GO; GO:1990246; C:uniplex complex; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR GO; GO:0036444; P:calcium import into the mitochondrion; IBA:GO_Central.
DR GO; GO:0051560; P:mitochondrial calcium ion homeostasis; IBA:GO_Central.
DR CDD; cd15900; EFh_MICU; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR039800; MICU1/2/3.
DR PANTHER; PTHR12294; EF HAND DOMAIN FAMILY A1,A2-RELATED; 1.
DR PANTHER; PTHR12294:SF13; MITOCHONDRIAL CALCIUM UPTAKE 3, ISOFORM D; 1.
DR Pfam; PF00036; EF-hand_1; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 1: Evidence at protein level;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Proteomics identification {ECO:0007829|EPD:D9N139,
KW ECO:0007829|PeptideAtlas:D9N139};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 166..201
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 405..432
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 458 AA; 52766 MW; C8AE6652C8A9BEFE CRC64;
MKRVLSRFWG FSTKHRQHIL NQRIVERTSA RNVAVLTAAG IGTSIGAYQL IDTARAGILD
GSDDASRHNV TTDHKLTKRE LRFLQFASVE YDDVIYMSPM DFIDSLTLDA PRERVYRRVL
KEKDIQRILK KTPPFRSGGK HFFRTMDQSG IISYSEYIFL LTLLTKSKAA FRIAFLMFDE
DDNGNIDRDE FMLIRSLTSS LRSTTRVQPS TASDEEDRRE SCQLDAADYH FAVSRIGADR
LFTGADSYAV MFTKSEEEVR KQDTTLLLHL FGLRGNATLS FDEFQQFYEN LQEELMEIEF
YEFARGKTAI SPVDFARLIL RYSIVNFDDY HKYLQRVQEK SDDDEPGISL SQWATFSRFL
NNLAEFQSAV RLYVNSNVPV SEPEFARAVG CTIGKELDPV VVSMIFRIFD ENNDGTLSYP
EFLAVMSDRL HRGLRGRLEK PWGWKPFKNC VISEVSRA
//
