ID D9QE17_CORP2 Unreviewed; 671 AA.
AC D9QE17;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Succinate dehydrogenase (Quinone) flavoprotein subunit {ECO:0000313|EMBL:ADL09740.1};
DE EC=1.3.5.1 {ECO:0000313|EMBL:ADL09740.1};
GN Name=sdhA {ECO:0000313|EMBL:ADL09740.1};
GN ORFNames=CPC231_01250 {ECO:0000313|EMBL:ADL09740.1};
OS Corynebacterium pseudotuberculosis (strain C231).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=681645 {ECO:0000313|EMBL:ADL09740.1, ECO:0000313|Proteomes:UP000000276};
RN [1] {ECO:0000313|EMBL:ADL09740.1, ECO:0000313|Proteomes:UP000000276}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C231 {ECO:0000313|EMBL:ADL09740.1,
RC ECO:0000313|Proteomes:UP000000276};
RX PubMed=21037006; DOI=.1128/JB.01211-10;
RG Consortium: Rede Paraense de Genomica e Proteomica (RPGP);
RA Silva A., Schneider M.P., Cerdeira L., Barbosa M.S., Ramos R.T.,
RA Carneiro A.R., Santos R., Lima M., D'Afonseca V., Almeida S.S.,
RA Santos A.R., Soares S.C., Pinto A.C., Ali A., Dorella F.A., Rocha F.,
RA de Abreu V.A., Trost E., Tauch A., Shpigel N., Miyoshi A., Azevedo V.;
RT "Complete genome sequence of Corynebacterium pseudotuberculosis I19, a
RT strain isolated from a cow in Israel with bovine mastitis.";
RL J. Bacteriol. 193:323-324(2011).
RN [2] {ECO:0000313|EMBL:ADL09740.1, ECO:0000313|Proteomes:UP000000276}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C231 {ECO:0000313|EMBL:ADL09740.1,
RC ECO:0000313|Proteomes:UP000000276};
RX PubMed=21533164; DOI=10.1371/journal.pone.0018551;
RA Ruiz J.C., D'Afonseca V., Silva A., Ali A., Pinto A.C., Santos A.R.,
RA Rocha A.A., Lopes D.O., Dorella F.A., Pacheco L.G., Costa M.P., Turk M.Z.,
RA Seyffert N., Moraes P.M., Soares S.C., Almeida S.S., Castro T.L.,
RA Abreu V.A., Trost E., Baumbach J., Tauch A., Schneider M.P., McCulloch J.,
RA Cerdeira L.T., Ramos R.T., Zerlotini A., Dominitini A., Resende D.M.,
RA Coser E.M., Oliveira L.M., Pedrosa A.L., Vieira C.U., Guimaraes C.T.,
RA Bartholomeu D.C., Oliveira D.M., Santos F.R., Rabelo E.M., Lobo F.P.,
RA Franco G.R., Costa A.F., Castro I.M., Dias S.R., Ferro J.A., Ortega J.M.,
RA Paiva L.V., Goulart L.R., Almeida J.F., Ferro M.I., Carneiro N.P.,
RA Falcao P.R., Grynberg P., Teixeira S.M., Brommonschenkel S., Oliveira S.C.,
RA Meyer R., Moore R.J., Miyoshi A., Oliveira G.C., Azevedo V.;
RT "Evidence for reductive genome evolution and lateral acquisition of
RT virulence functions in two Corynebacterium pseudotuberculosis strains.";
RL PLoS ONE 6:E18551-E18551(2011).
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DR EMBL; CP001829; ADL09740.1; -; Genomic_DNA.
DR RefSeq; WP_013241102.1; NC_017301.2.
DR AlphaFoldDB; D9QE17; -.
DR STRING; 681645.CpC231_0246; -.
DR GeneID; 69458471; -.
DR KEGG; cpq:CPC231_01250; -.
DR PATRIC; fig|681645.3.peg.253; -.
DR eggNOG; COG1053; Bacteria.
DR HOGENOM; CLU_014312_7_0_11; -.
DR OrthoDB; 9805351at2; -.
DR Proteomes; UP000000276; Chromosome.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR GO; GO:0008152; P:metabolic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ADL09740.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000276}.
FT DOMAIN 63..472
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 536..670
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 361
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 671 AA; 74638 MW; AD8B5F24AFF4CFC5 CRC64;
MSFNSETATR PEFTQPASIV DGVKLGSILE SNEPKGVPTK DMWEYQKDHM NLVSPLNRRK
FTVLVVGTGL SGGGAAAALG ELGYNVKVFT YHDAPRRAHS IAAQGGVNSA RGKKVDNDGA
YRHVKDTVKG GDYRCRESDC WRLAYESVRV IDHMNAIGAP FAREYGGTLA TRSFGGVQVS
RTYYTRGQTG QQLQLSGAAA LQRQIGLGTV EIFTHADMHD LILTDENGKK ACRGIVTRNL
ITGELTPHTG HAVILATGGY GNVYHMSTLA KNSNASAMMR AYELGAYLAS PSFIQFHPTG
LPVNSEWQSK TILMSESLRN DGRIWSPLEP KDDRDPNTIP EEERDYFLER RYPAFGNLVP
RDVASRAISQ QINKGLGVGP LHNSAYLDFR DSIERLGENT IRERYSNLFQ MYEEAIGENP
FKAPMRIAPT CHFTMGGLWT DFNEMTSIDG LFAAGECSWT YHGANRLGAN SLLSASVDGW
FTLPFTIPNY LANHLGEAKL AEDAPEAVAA VARAQARIDK LMNIKGDDPH GPEHYHRQLG
DILYFSCGVA RNVEDLKTGI EKIRKLRKEF WSNLRITGEA EEMNQVLEYA CRVADYIDLG
ELMCVDALDR DESCGAHFRE DHLSSEGEAE RDDENWCFVS AWEPGAQEHE FIRHAEPLTF
ESIPLMTRNY K
//
