ID D9SP18_CLOC7 Unreviewed; 630 AA.
AC D9SP18;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=NADH dehydrogenase (Quinone) {ECO:0000313|EMBL:ADL51983.1};
DE EC=1.6.99.5 {ECO:0000313|EMBL:ADL51983.1};
GN OrderedLocusNames=Clocel_2244 {ECO:0000313|EMBL:ADL51983.1};
OS Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=573061 {ECO:0000313|EMBL:ADL51983.1, ECO:0000313|Proteomes:UP000002730};
RN [1] {ECO:0000313|EMBL:ADL51983.1, ECO:0000313|Proteomes:UP000002730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35296 / DSM 3052 / OCM 3 / 743B
RC {ECO:0000313|Proteomes:UP000002730};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA Hemme C.L., Woyke T.;
RT "Complete sequence of Clostridium cellulovorans 743B.";
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
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DR EMBL; CP002160; ADL51983.1; -; Genomic_DNA.
DR RefSeq; WP_010076790.1; NC_014393.1.
DR AlphaFoldDB; D9SP18; -.
DR STRING; 573061.Clocel_2244; -.
DR KEGG; ccb:Clocel_2244; -.
DR eggNOG; COG1894; Bacteria.
DR HOGENOM; CLU_014881_3_2_9; -.
DR OrthoDB; 9761899at2; -.
DR Proteomes; UP000002730; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01257; 2Fe-2S_thioredx; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF13187; Fer4_9; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:ADL51983.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002730}.
FT DOMAIN 572..602
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 603..630
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 630 AA; 68867 MW; 7B3C13AC32A3ADAB CRC64;
MEKIKSYSEL NLFHKECRKL LSLRYSEDVE KSKDNKKDKI EVLVCGGTGC KSSNSDEIIK
NFKLEIENIN LSSKVSVKMT GCFGFCEKGP IVKIIPDNTF YIHVSPKDVA EIVEEHIING
NIVDRLLYEE PTLKEKITKQ EEMSFYKKQR RIALKNCGVI DPEDIKEYIG AKGYLALGKV
INEMTPEDVI KEITDSGLRG RGGGGFPTGK KWSLAKDSKD DIKYIICNAD EGDPGAFMDR
AILEGDPNSI IEAMAIAGYA IGASKGLIYI RAEYPLAVQR LMIAIEQAKE IGVIGEGILG
SSFNFDVEIK YGAGAFVCGE ETALVHSIEG CRGEPTTKPP FPAEKGLFNK PTSVNNVETF
ANITAIINNG SQWFSSIGTN TSKGTKVFAL AGKIKNVGLV EVPMGIKLEE IIYEIGGGIK
DNKEFKAVQT GGPSGGCIPS MLLDLPIDYE SLNAVGSMMG SGGMIVMDED DCMVDIAKFY
LEFIVDESCG KCTPCRVGNK RLLEILNKIV EGKGTEDDIK KLKDLSKVIK DTALCGLGQT
APNPILSTMT YFMDEYNAHV DEKKCVAGKC KKLVRYEITD ECIGCTKCSR ACPVRCISGK
IKGKHIIDQE KCIKCGTCFE GCPVKAIKLG
//
