ID D9SW08_CLOC7 Unreviewed; 249 AA.
AC D9SW08;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Competence protein ComEA helix-hairpin-helix repeat protein {ECO:0000313|EMBL:ADL51152.1};
GN OrderedLocusNames=Clocel_1399 {ECO:0000313|EMBL:ADL51152.1};
OS Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=573061 {ECO:0000313|EMBL:ADL51152.1, ECO:0000313|Proteomes:UP000002730};
RN [1] {ECO:0000313|EMBL:ADL51152.1, ECO:0000313|Proteomes:UP000002730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35296 / DSM 3052 / OCM 3 / 743B
RC {ECO:0000313|Proteomes:UP000002730};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA Hemme C.L., Woyke T.;
RT "Complete sequence of Clostridium cellulovorans 743B.";
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002160; ADL51152.1; -; Genomic_DNA.
DR RefSeq; WP_010075985.1; NC_014393.1.
DR AlphaFoldDB; D9SW08; -.
DR STRING; 573061.Clocel_1399; -.
DR KEGG; ccb:Clocel_1399; -.
DR eggNOG; COG1555; Bacteria.
DR HOGENOM; CLU_052011_1_2_9; -.
DR OrthoDB; 9790239at2; -.
DR Proteomes; UP000002730; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 1.10.150.320; Photosystem II 12 kDa extrinsic protein; 1.
DR InterPro; IPR004509; Competence_ComEA_HhH.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR NCBIfam; TIGR00426; competence protein ComEA helix-hairpin-helix repeat region; 1.
DR PANTHER; PTHR21180; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR21180:SF32; ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF12836; HHH_3; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00278; HhH1; 2.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002730};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 196..215
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT DOMAIN 226..245
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT REGION 45..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..61
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..85
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 249 AA; 27549 MW; 33D73A943E0BB27E CRC64;
MDKNKKLIGS ITVVILLVIM MAVGYKLSQP KVITDKDMEV MIDTSEDSSF QKESLNVENQ
QENKQENKRE NTEESQSKVD DSKKQGSSKI VVQVQGEVKN PGIYDLDEGS RIRDLIEAAG
GLTENADKTI NQALKLKDED SVVVYKVGDH IENAVAVNNI ISSNNSAGSN NKKGDDKGTS
TEKTDVKVDI NTATKEQLMS LKGIGETYSE KIIEYREKNG PFKTIEELKN VSGIGEKTFE
KIKDSIEVK
//
