ID D9VZL4_9ACTN Unreviewed; 232 AA.
AC D9VZL4;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE RecName: Full=Cobalt transport protein CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
DE AltName: Full=Energy-coupling factor transporter probable substrate-capture protein CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
DE Short=ECF transporter S component CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
GN Name=cbiM {ECO:0000256|HAMAP-Rule:MF_01462};
GN ORFNames=SSNG_05012 {ECO:0000313|EMBL:EFL17760.1};
OS Streptomyces sp. C.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=253839 {ECO:0000313|EMBL:EFL17760.1, ECO:0000313|Proteomes:UP000005763};
RN [1] {ECO:0000313|EMBL:EFL17760.1, ECO:0000313|Proteomes:UP000005763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C {ECO:0000313|EMBL:EFL17760.1,
RC ECO:0000313|Proteomes:UP000005763};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "Annotation of Streptomyces sp. strain C.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the energy-coupling factor (ECF) transporter complex
CC CbiMNOQ involved in cobalt import. {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- SUBUNIT: Forms an energy-coupling factor (ECF) transporter complex
CC composed of an ATP-binding protein (A component, CbiO), a transmembrane
CC protein (T component, CbiQ) and 2 possible substrate-capture proteins
CC (S components, CbiM and CbiN) of unknown stoichimetry.
CC {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01462};
CC Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01462}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CbiM family. {ECO:0000256|HAMAP-
CC Rule:MF_01462}.
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DR EMBL; GG657750; EFL17760.1; -; Genomic_DNA.
DR RefSeq; WP_007266687.1; NZ_GG657750.1.
DR AlphaFoldDB; D9VZL4; -.
DR STRING; 253839.SSNG_05012; -.
DR eggNOG; COG0310; Bacteria.
DR HOGENOM; CLU_052508_3_0_11; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000005763; Unassembled WGS sequence.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.1760.20; -; 1.
DR HAMAP; MF_01462; CbiM; 1.
DR InterPro; IPR018024; CbiM.
DR InterPro; IPR002751; CbiM/NikMN.
DR NCBIfam; TIGR00123; cbiM; 1.
DR PANTHER; PTHR43627; -; 1.
DR PANTHER; PTHR43627:SF1; COBALT TRANSPORT PROTEIN CBIM; 1.
DR Pfam; PF01891; CbiM; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Cobalt {ECO:0000256|ARBA:ARBA00023285, ECO:0000256|HAMAP-Rule:MF_01462};
KW Cobalt transport {ECO:0000256|ARBA:ARBA00022426, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01462};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01462}.
FT TRANSMEM 41..58
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 79..102
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 108..127
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 139..161
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 181..204
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
SQ SEQUENCE 232 AA; 24023 MW; 7B0774ED84789344 CRC64;
MHIAEGFLPP LHAAAWGAAS APFVVHGVRA LTREVKANPE STLLLGASGA FTFVLSALKI
PSVTGSCSHP TGTGLGAILF RPPIMAVLGT ITLLFQALLL AHGGLTTLGA NVFSMAVAGP
WAGYGVYRLL RKSGAPLMVT VFFGAFFADL VTYCVTSVQL ALAFPDPASG FLGSLEKFAG
IFALTQIPLA ISEGLLTVLV MRLLMQSSKS DLVRLGVAKL TGGKQAKQEA AL
//
