ID D9WJ07_9ACTN Unreviewed; 590 AA.
AC D9WJ07;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Long-chain-fatty-acid-CoA ligase {ECO:0000313|EMBL:EFL27660.1};
GN ORFNames=SSOG_07374 {ECO:0000313|EMBL:EFL27660.1};
OS Streptomyces himastatinicus ATCC 53653.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group.
OX NCBI_TaxID=457427 {ECO:0000313|EMBL:EFL27660.1, ECO:0000313|Proteomes:UP000003963};
RN [1] {ECO:0000313|EMBL:EFL27660.1, ECO:0000313|Proteomes:UP000003963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53653 {ECO:0000313|EMBL:EFL27660.1,
RC ECO:0000313|Proteomes:UP000003963};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "Annotation of Streptomyces hygroscopicus strain ATCC 53653.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG657754; EFL27660.1; -; Genomic_DNA.
DR RefSeq; WP_009719458.1; NZ_GG657754.1.
DR AlphaFoldDB; D9WJ07; -.
DR STRING; 457427.SSOG_07374; -.
DR HOGENOM; CLU_000022_59_7_11; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000003963; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:EFL27660.1}.
FT DOMAIN 27..426
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 476..551
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT REGION 558..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 61852 MW; B64DA85825E7542F CRC64;
MTDYWPAGLP RHLDYPDVPL GAVLAGSARR YGDRAALRDG DQVLTFTGLY EQAAAFAGGL
RAHGIRQGDV VALHLPNTLW FAVAYYGIAL AGATACPANP AQPAKALRAQ LADCSAAAVV
THPQPAPVLA EAIGGLPVRL VVIVPPSESA PADRPDDCTK LFGEAGTALE SLVAGQSTHP
PEVLVPTDSV AQYGYTGGTT GAPKGVRILH RNIVGNTIQV ACWRAGALPG LDSDGGVVLH
PLGTSGDSAL PLGSCTALCV SPLFHALGLI SLNFFLLCGA TTILNGRFDA ESYLEQVERH
RITYIPGAPA LWHALLATPG IRTRNLSSVK AVVSGGAPMD AYALEKLTEV FPNAAVIEGY
GLTEATATVS SGPIAKAGLH KPGSQGVPLF DTQLEIRDPL RPGRKVPRGE RGEIWARGPQ
VAAGYLGRPD ETAAQFVDGW LCTGDIGHLD EDGFLYVSGR SKDMLIYKGY NVYPRELEDI
LGGHPAVLQA SVVGKEVPAV GEIPVAFVVP ASERGTSAEE LMEYVAERVT PYKRIREIRF
VAALPLSPAG KVLKSELRRL ARTTGDPGAS PSGTQETGAP DAAGEQVRHA
//
