ID D9WNC5_9ACTN Unreviewed; 597 AA.
AC D9WNC5;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Putative NAD dependent epimerase/dehydratase family protein {ECO:0000313|EMBL:EFL23822.1};
GN ORFNames=SSOG_03536 {ECO:0000313|EMBL:EFL23822.1};
OS Streptomyces himastatinicus ATCC 53653.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group.
OX NCBI_TaxID=457427 {ECO:0000313|EMBL:EFL23822.1, ECO:0000313|Proteomes:UP000003963};
RN [1] {ECO:0000313|EMBL:EFL23822.1, ECO:0000313|Proteomes:UP000003963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53653 {ECO:0000313|EMBL:EFL23822.1,
RC ECO:0000313|Proteomes:UP000003963};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "Annotation of Streptomyces hygroscopicus strain ATCC 53653.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG657754; EFL23822.1; -; Genomic_DNA.
DR RefSeq; WP_009715637.1; NZ_GG657754.1.
DR AlphaFoldDB; D9WNC5; -.
DR STRING; 457427.SSOG_03536; -.
DR HOGENOM; CLU_030014_0_0_11; -.
DR OrthoDB; 5241256at2; -.
DR Proteomes; UP000003963; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR013120; Far_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48079; PROTEIN YEEZ; 1.
DR PANTHER; PTHR48079:SF6; PROTEIN YEEZ; 1.
DR Pfam; PF12697; Abhydrolase_6; 1.
DR Pfam; PF07993; NAD_binding_4; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
FT DOMAIN 13..235
FT /note="Thioester reductase (TE)"
FT /evidence="ECO:0000259|Pfam:PF07993"
FT DOMAIN 371..589
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF12697"
SQ SEQUENCE 597 AA; 63911 MW; 5100BC41CD21FCE7 CRC64;
MSVVEDRHAL VLGATGFLGR HLVLALGRAG VRVSTASRSH ESYRRLARWL AEQGHGHETA
PADLRVDFAE PSLIQGECDD VTEIYNCAGA YRFGMSADDA HRANVDSVRA VVAFAAQLPR
LRRLVHVSGY RVGGQDPALW SDERRAAAYR ALGPYEASKA EADAVFQVVA DELGVPWSIV
SPASVIGDSV TGESDQYLGL ASSVKDLWRG SLPALPGNAS TFVPVVAADY LARFMSLLPL
DDAAERASYW LLDDDTPPLP DLLTLIAEHY RITAPRVRIP VSLVKRLPRR LTKADPETLT
FLSSDRYPTA SAHAFAARHG LTMPDAVTTI RRWADHLAAH RFGDAPADDR RFTTPGGIRT
FELGDAAAPT VVMPGLPVNA DTWAPVVTAM GGARAVDLPG LGMSGGHRDD WPTWLSALIT
ETGARHLVGH SIGAAAAVEA AAAHPGAVER LTLVAPYFLQ ARPAPTIQWA PLTRGYLSHV
SPEALAKRLT GTTEHASALR SSVADLRRGT VAANVSRLLA AAAKPRWRED LRAELRHYPG
RVHVIVGSHD PLTPDGRALL DALPHATVTV VEGAGHQLQL THPEEVAKAI ASVSIAP
//
