ID D9WVC6_9ACTN Unreviewed; 422 AA.
AC D9WVC6;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Putative polyketide beta-ketoacyl synthase 2 {ECO:0000313|EMBL:EFL22303.1};
GN ORFNames=SSOG_02015 {ECO:0000313|EMBL:EFL22303.1};
OS Streptomyces himastatinicus ATCC 53653.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group.
OX NCBI_TaxID=457427 {ECO:0000313|EMBL:EFL22303.1, ECO:0000313|Proteomes:UP000003963};
RN [1] {ECO:0000313|EMBL:EFL22303.1, ECO:0000313|Proteomes:UP000003963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53653 {ECO:0000313|EMBL:EFL22303.1,
RC ECO:0000313|Proteomes:UP000003963};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "Annotation of Streptomyces hygroscopicus strain ATCC 53653.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
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DR EMBL; GG657754; EFL22303.1; -; Genomic_DNA.
DR RefSeq; WP_009714124.1; NZ_GG657754.1.
DR AlphaFoldDB; D9WVC6; -.
DR STRING; 457427.SSOG_02015; -.
DR HOGENOM; CLU_000022_69_2_11; -.
DR OrthoDB; 416758at2; -.
DR Proteomes; UP000003963; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR CDD; cd00832; CLF; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF322; POLYKETIDE BETA-KETOACYL SYNTHASE 2-RELATED; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 15..417
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 422 AA; 44202 MW; 73532DDA40596644 CRC64;
MNATVETTSR ARKHIRGAAI TGMGIVAPNG VGTDAFWKGV REGITFLDRL TREGCEDSPL
RIAGQVRGFE PGSVVEERYL VQTDRFTHFA MTAAELALDD ARLPRKDMSP YAVGVVTASG
SGGGEFGQRE LQQLWGKGPR YVGPYQSIAW FYAASTGQIS IRGGFKGPCG VVANDEAGGL
DALAHACRSI RHGADAIVVG AAEAPLAPYS VVCQLGYEEM SLARDAGRAY LPFTADACGF
APGEGGAMLI VEEEGAALRR GARVRGRILG HGATFTGPSM WERSREGLAQ AIRVALDEAE
CAPEEIDVVF ADALGTPEAD RAEALAIADA LGAHGTRVPV TAPKTGFGRA YCAAPVLDVA
SAVLAMEHRV VPPTPYVTDV CHDLDLVTGS SRACGARTAL VLSRGLMGCN AALVLRGPEG
DM
//
