ID   D9XKE4_9ACTN            Unreviewed;       415 AA.
AC   D9XKE4;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=Aromatic-ring hydroxylase {ECO:0000313|EMBL:EFL43170.1};
GN   ORFNames=SSRG_05974 {ECO:0000313|EMBL:EFL43170.1};
OS   Streptomyces griseoflavus Tu4000.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=467200 {ECO:0000313|EMBL:EFL43170.1, ECO:0000313|Proteomes:UP000002968};
RN   [1] {ECO:0000313|EMBL:EFL43170.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tu4000 {ECO:0000313|EMBL:EFL43170.1};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA   Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA   Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA   Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA   Haas B., Nusbaum C., Birren B.;
RT   "Annotation of Streptomyces griseoflavus strain Tu4000.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG657758; EFL43170.1; -; Genomic_DNA.
DR   AlphaFoldDB; D9XKE4; -.
DR   STRING; 467200.SSRG_05974; -.
DR   eggNOG; COG0654; Bacteria.
DR   HOGENOM; CLU_009665_19_3_11; -.
DR   Proteomes; UP000002968; Unassembled WGS sequence.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProt.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR002938; FAD-bd.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR13789; MONOOXYGENASE; 1.
DR   PANTHER; PTHR13789:SF309; PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED; 1.
DR   Pfam; PF01494; FAD_binding_3; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
FT   DOMAIN          2..342
FT                   /note="FAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01494"
SQ   SEQUENCE   415 AA;  45280 MW;  BBA75EDB9DACE3D7 CRC64;
     MVGGGIGGLG VACSLTRQGQ SVRLLESAPA FGEVGAGIQL APNCTRILDD YGLLDEAKSL
     GVVPDAMVMR DAVDGEELTR LDLRDLERRY GYPYLVIHRS DLHGLLLRAC ERAGVELVND
     ARVTSYENTD GGARVTLASG ETHEAGMVIA ADGLHSPARK LFVDDRPVSS AYVAYRGTVP
     AAQPRVKSVD LSEVVVYIGP RCHFVHYGLR GGEMLNQVAV FESPKALAGH DDWGTPDELD
     AAFAGTCGFV QDGLPFMWRD KWWRMFDRDP IMTWVHGRIA LLGDSAHPPL QYIAQGAIMA
     VEDGWVLGEH VARNRAEDGT VDWTAALAAY EAVRPEHCRR VLTTSRKWGE LWHLDGLARE
     QRNVLLRARD TYDYAFTDWL YGPTALTPDE EPPMFTAIPL DSAVTGEPVP AGGAA
//